Progressive Progressive Medical Center - 2019 | Page 25

and the cells burn through nutrients. Diffuse hair loss may also be seen in this condition, along with body hair loss. Unlike hypothyroid, persons with high thyroid hormones tend to have increased appetite, weight loss, and insomnia. giving birth, these hormones and growth factors drop off sharply which triggers hair loss. Fortunately, this is largely self-limiting, and normal hair growth resumes. Treating hyperthyroid conventionally involves the thyroid- blocking medication methimazole. Often, hyperthyroid is part of an autoimmune condition and may spontaneously remit within a year. Once thyroid hormone levels are brought down to a normal level, hair loss should stop. Patchy hair loss may be caused by a fungal infection of the head, called tinea capitis. The fungus lives deep enough in the skin to cause hair loss, but not so deep as to trigger the immune system. Fungal infections can happen anywhere on the body, and normally cause patches of itching and some skin peeling. Topical antifungals work well, and hair normally returns to normal thickness after the infection is resolved. ANDROGEN EXCESS Testosterone is the most renown of androgens, but there are actually many different androgens, all of which have different actions. The type of androgen classically responsible for hair loss is called dihydrotestosterone (DHT). This hair loss pattern tends to present in the classic “male pattern balding,” with hair loss coming mainly from the front and the top of the head. This is a bit of a misnomer, because women can also experience this type of hair loss. Medications that block the conversion of testosterone to DHT — like finasteride or minoxidil — are often a first-line treatment for androgen-related hair loss. However, once the drug is stopped, hair loss resumes. There are also nonpharmaceutical substances that block the formation of DHT, like saw palmetto 1 and zinc 2 . Other strategies include supporting hormone balance and excretion. AUTOIMMUNE Alopecia areata is the most common autoimmune cause of hair loss. It presents with circular patches of hair loss, which may converge or eventually include the whole head. This disease tends to remit spontaneously. Treatment involves addressing the underlying immune dysfunction and inflammation. There have been several positive studies on the efficacy of onion juice therapy to aid hair regrowth. 3,4 Other autoimmune conditions that may cause hair loss include lupus, lichen planus, and alopecia totalis (also known as alopecia universalis). Often, autoimmune conditions present with systemic symptoms like fevers, weight loss, and fatigue. NUTRITIONAL DEFICIENCY Hair cells replicate very quickly, much like our skin cells. This means that they need a lot of nutrients and are often the first to reflect any nutrient deficiencies. Hair growth may slow, strands may break easily, and hair may even thin. Anyone on a proton pump inhibitor like Prilosec is at risk for nutritional deficiencies, because stomach acid is essential for freeing minerals for absorption. If nutrient deficiency is the underlying reason for hair loss, the nails may also reflect this. Peeling, thin, and easily broken nails are signs of general nutrient deficiency. White spots on the nails, if not from trauma, are often a sign of zinc deficiency. POSTPARTUM During pregnancy, a woman has a lot of extra hormones and growth factors, which drive hair growth. After INFECTIONS 1. Marks, L. S., Hess, D. L., Dorey, F. J., Macairan, M. L., Santos, P. B. C., & Tyler, V. E. (2001). Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens. Urology, 57(5), 999-1005. 2. Azzouni, F., Godoy, A., Li, Y., & Mohler, J. (2012). The 5-alpha-reductase isozyme family: a review of basic biology and their role in human diseases. Advances in urology, 2012. 3. Sharquie, K. E., & Al Obaidi, H. K. (2002). Onion juice (Allium cepa L.), a new topical treat- ment for alopecia areata. The Journal of dermatology, 29(6), 343-346. 4. Hajheydari, Z., Jamshidi, M., Akbari, J., & Mohammadpour, R. (2007). Combination of topical garlic gel and betamethasone valerate cream in the treatment of localized alopecia areata: a double-blind randomized controlled study. Indian Journal of Dermatology, Venereology, and Leprology, 73(1), 29. SIGNS OF HYPOTHYROIDISM • COLD HANDS AND FEET • UNEXPLAINED WEIGHT GAIN OR INABILITY TO LOSE WEIGHT • DRY SKIN • BRITTLE NAILS • FATIGUE • CONSTIPATION • SLOW HEART RATE • LOW TEMPERATURE • BRAIN FOG CAUSES OF NUTRITIONAL DEFICIENCY PROTON PUMP INHIBITOR • PROFUSE SWEATING • FREQUENT DIARRHEA • FREQUENT VOMITING • GROWING (KIDS) • PREGNANCY • POOR OR UNVARIED DIET • EXERCISE • 25