PPMI | Page 7

Dear PPMI Participant, Thank you for all you are doing to make PPMI possible. Planning for this study began in 2007 and, while we successfully galvanized the expertise and funding to launch the study in 2010, this study would not be where it is today without you. As a result of your participation in PPMI, we are now amassing the largest data bank and biorepository in the history of Parkinson’s disease (PD) research. Scientists from around the world are accessing what we are building in PPMI, and it’s all thanks to you. In addition to the PD research community, others are taking notice of your efforts. Other disease states, media outlets, and the PD community are increasingly interested in PPMI’s structure and success and are eager to share in our lessons learned and scientific findings. When we launched PPMI in 2010, a PD research study of this size and scope had never even been attempted. All we could do next was open the clinic doors and wait to see if anyone would sign up to participate. Your response and willingness to contribute your time and energy have been and continue to be nothing short of amazing. Together, we are truly making PD research history. Thank you for being a part of PPMI. PPMI Principal Investigator Ken Marek, MD and the PPMI Steering Committee 3