OPTICAL PRODUCT
Next-Gen Photonics Instruments
NEXT-GEN PHOTONICS INSTRUMENTS FOR BIOIMAGING AND SPECTROSCOPY
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Antonio CASTELO * 17 Rue Hamelin, 75016 Paris, France * antonio. castelo @ epic-photonics. com
https:// doi. org / 10.1051 / photon / 202513472
Photonics has revolutionized the life sciences by providing powerful, non-invasive tools for observing, measuring, and manipulating biological systems with exceptional precision and sensitivity. Imaging techniques such as optical microscopy, fluorescence imaging or optical coherence tomography enable researchers and clinicians to study cells, tissues, and molecular interactions in real time and in their natural environments. And spectroscopy of biological samples enables the non-invasive investigation of molecular composition, structure, and dynamics within cells, tissues, and biofluids. These technologies are essential for early disease diagnosis, drug development, neuroscience, genomics, and personalized medicine.
Recent advances in photonics are pushing the boundaries of what’ s possible in bioimaging and spectroscopic analysis of biological samples. New developments in light sources and detectors are opening exciting frontiers in sensitivity, speed, and spectral coverage. The latest LEDs technologies bring greater flexibility, brightness, and depth performance to bioimaging and spectroscopic tools, enabling new capabilities in noninvasive diagnostics, functional imaging, and real-time molecular sensing. Quantum dots detectors, along with enhanced readout electronics and integrated multiplexing, are and exciting development which enables the next-generation of imaging systems to capture weak signals and resolve fast dynamics. And the most recent optical components are being tailored to biological samples and to optimize the illumination and the performance of the imaging systems.
NEW DEVELOPMENTS IN FLUORESCENCE MICROSCOPY Fluorescence microscopy is a cornerstone of modern biological and biomedical research. This technology offers unparalleled sensitivity and specificity for visualizing structures and processes within cells and tissues. By tagging molecules with fluorescent markers, researchers can observe the localization, dynamics, and interactions of proteins, nucleic acids, and other biomolecules in real time, often at the single-molecule level. This ability to illuminate specific
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