Pharmacy News December 2018 | Page 25

Dec 2018 25 F Cr Feature Review Clinical Table 1. History-taking in allergic rhinitis (AR) Important feature of the history Significance General When did the symptoms first start? Persistent (previously perennial), AR is more common in preschool-aged children. Intermittent AR with a seasonal variance is more common in school-aged children and young adults. Onset in later life should prompt consideration of a non-allergic cause of rhinitis. Do the symptoms occur predominantly at certain times of the year or all year round? In general, grasses pollinate late-spring to early-summer and trees do so from late- winter to early spring. What indoor allergens is the patient exposed to? Understanding a patient’s housing and workplace conditions will reveal potential offending allergens. What is the patient’s occupation? Understanding a patient’s housing and workplace conditions will reveal potential offending allergens. Is there a family history of atopy? A family history of atopy and in particular AR is the best-established risk factor for the development of AR. What is the impact of symptoms? AR can have a significant, negative impact on sleep quality and other quality of life domains. What medications have been tried to date? How regularly and for how long? Failure of response to particular medications helps direct initial pharmacotherapy. Failure of response to an optimal regimen of medications may suggest an alternative cause.Prolonged use of nasal decongestants can lead to rebound rhinitis (see rhinitis medicamentosa). What other medications does the patient take regularly? Drug-induced rhinitis (see differential diagnosis) may mimic allergic rhinitis. Symptoms Classification Classifying AR helps direct initial pharmacotherapy. What is the most troublesome symptom? The predominant symptom may potentially direct treatment. What is the character and source of nasal discharge? Consider ‘red flags’. Is there a diurnal variation to symptoms? Sneezing and nasal obstruction are worse in the morning in 70% of patients with AR. Is there hyposmia or anosmia? Mild hyposmia is not rare in symptomatic AR; however, anosmia or more severe hyposmia should prompt consideration of alternative diagnosis. Is post-nasal drip or chronic cough a feature? This question may reveal acute or chronic sinusitis as a concomitant or alternative diagnosis (see differential diagnosis). Are there symptoms consistent with asthma or bronchial hypersensitivity? The close relationship between AR and asthma is discussed later. History-taking in a patient presenting with AR should aim to determine the presence and degree of concomitant asthma. Source: AIHW and Hu W, et al. Allergic rhinitis: practical management strategies. Australian Family Physician 2008; 37:214-20. The nose Rhinorrhoea is often appreciable during examination and the character of the discharge should be noted. Examination of the nose much beyond the nares is difficult without specialised equipment, and adequate lighting from a simple head lamp, at the very least, is essential. A Thudichum or other nasal speculum will open the nare and aid in examination. Enlarged, red-to-purple inferior turbinates with vascular dilatation and obvious limitation of the nasal airway is characteristic of allergic rhinitis. Nasal polyps are not usually appreciated on anterior rhinoscopy. Further examination of the nose requires flexible or rigid nasendoscopy, which allows a full examination of the nasal cavity, the adenoids and beyond. Nasal airflow should be assessed during examination. Ask the patient to breathe in and out through the nose, and repeat the exercise with the left then right nare occluded. During this assessment, ask the patient if any manoeuvres or manipulation of the nose improves breathing, which may give clues to alternative or exacerbating causes of nasal obstruction such as nasal valve collapse. The head and neck Examine the head and neck for any evidence of regional infection that may direct further examination and investigation. The chest Given the close relationship between allergic rhinitis and asthma, examination is incomplete without inspection of the chest for evidence of obstructive airways disease and auscultation for wheeze. Differential diagnosis There are myriad conditions that mimic one or more of the symptoms of allergic rhinitis,