PECM Issue 45 2020 | Page 60

NEWS & EVENTS AUTOMATED QUALITY CONTROL OIA Quality assurance detection rate up by x30 for inhaler manufacture The leak detection rate for in-line pharmaceutical gas analysis during inhaler production has increased by 30 times following the introduction of a new automated quality control solution. The robotised system for Metered Dose Inhaler (MDI) manufacture built by Optimal Industrial Automation means significantly reduced cost and wastage in quality control for MDI manufacture. It’s essential that MDI canisters, typically used in asthma type inhalers, are produced with an optimum level of gas propellant, but effective leak testing has traditionally been problematic. The MDI manufacturer’s objective was to implement 100% quality assurance of all cans while reducing cost and wastage. The company selected Optimal Industrial Automation to design a system based on its 30-year plus experience integrating high-speed and high accuracy quality control equipment. Optimal’s track record in resolving complex challenges with a range of high-profile brands within the pharmaceutical, chemical and food and beverage industries provided the confidence that an ideal solution could be found. Manufactured in vast volumes, MDI canisters are traditionally batch tested. The challenge for the manufacturer is that if a single canister is defective, the entire batch may be scrapped. This means potentially high wastage, increased cost and reduced efficiency of production. Instead, the manufacturer’s objective was to achieve testing of 100 per cent of canisters, meaning scrappage of only individually rejected MDIs. This was achieved thanks to Optimal’s design of a puck, robot and conveyor system with an integrated gas analyser. The pick and place action and synchronisation was provided by SCARA robots, a PLC and SCADA software from Mitsubishi Electric. “The application demands a high degree of accuracy to achieve the synchronisation required for a throughput of 180 cans per minute,” says Martin Gadsby, Director, Optimal Industrial Automation. “Reliability has been confirmed through extensive testing and we are now able to identify and reject individual canisters in a continuous process situation. This means significantly less wastage in manufacture and ultimately a reduced cost of production.” Optimal’s system runs on its own communication sub-net but communicates process flow signals both up and downstream. By leveraging an innovative automated quality control solution, which uses pucks, robot and conveyor systems with an integrated gas analyser, a meter dose inhaler (MDI) manufacturer increased the leak detection rate for in-line pharmaceutical gas analysis by 30 times. 60 PECM Issue 45