Orthopedics This Week | February 16, 2016 | Page 27

ORTHOPEDICS THIS WEEK
VOLUME 12, ISSUE 6 | FEBRUARY 16, 2016

across all indications including plaque
psoriasis (PsO).”
“For patients with AS, the MEASURE
2 study showed that patients treated
with 150 mg Cosentyx met the primary endpoint achievi ng statistically significant improvements versus placebo
in the signs and symptoms of AS, as
measured by at least a 20% improvement in the Assessment of Spondyloarthritis International Society criteria
(ASAS20) at Week 16.”
“Since treatment options for patients
with AS and PsA are limited, we’re
delighted that the FDA approved
Cosentyx for these additional indications just one year after the approval
for moderate-to-severe psoriasis.
These approvals provide an important
new option for those suffering from
these life-long, painful inflammatory
diseases.” — EH

27

Calcific Tendinitis
Involves Increased
Blood Vessel, Pain
Receptor Growth

A

new study appearing in February’s issue of the Journal of Bone
and Joint Surgery has found that calcific tendinitis of the shoulder involves a
significant increase in blood vessel and
pain receptor growth among patients
with this condition.
“We found a 3-to-8-fold increase in the
number of small blood vessels, nerves
and inflammatory cytokines (proteins
that direct cell growth) in patients with
calcific tendinitis in one of four rotator
cuff tendons, as compared to patients
with a torn yet normal tendon,” said
George A.C. Murrell, M.D., an Australian orthopedic surgeon and lead
author of the study, in the February 3,

Wikimedia Commons and elmundo

2016 news release. “This might explain
the chronic inflammation and severe
pain that patients with calcific tendinitis often experience.”
According to the news release, “In the
study, 30 patients received an ultrasound during arthroscopic surgery to
identify and remove samples of calcium within the shoulder tendon. Each
patient had calcific tendinitis, but no

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