Orthopedics This Week - 2018 | July 17, 2018

3 ORTHOPEDICS THIS WEEK VOLUME 14, ISSUE 23 | JULY 17, 2018 Robin Young’s Orthopedic Universe WORST PERFORMERS LAST 30 DAYS TOP PERFORMERS LAST 30 DAYS COMPANY 1 2 3 4 5 6 7 8 9 10 Aurora Spine AxoGen CryoLife Stryker Medtronic Johnson & Johnson Dynatronics Corp ConMed NuVasive Zimmer Biomet SYMBOL ASG.V AXGN CRY SYK MDT JNJ DYNT CNMD NUVA ZBH PRICE MKT CAP $0.12 $52.75 $29.65 $174.30 $88.36 $125.93 $3.04 $73.78 $53.89 $114.89 $5 $2,011 $1,086 $65,138 $119,437 $337,763 $25 $2,069 $2,762 $23,354 30-DAY CHG 31.53% 5.61% 5.33% 4.62% 2.94% 2.69% 1.84% 1.10% 0.80% 0.80% COMPANY 1 2 3 4 5 6 7 8 9 10 LOWEST PRICE / EARNINGS RATIO (TTM) COMPANY 1 2 3 4 5 Lattice Biologics MiMedx Group Johnson & Johnson Smith & Nephew Zimmer Biomet SYMBOL LBL.V MDXG JNJ SNN ZBH PRICE $0.05 $3.37 $125.93 $36.01 $114.89 1 2 3 4 5 MiMedx Group MicroPort Scientific Johnson & Johnson Integra LifeSciences Stryker SYMBOL MKT CAP P/E $4 $374 $337,763 $15,746 $23,354 9.72 17.06 19.72 20.53 21.40 MDXG 853 JNJ IART SYK PRICE MKT CAP $3.37 $1.19 $125.93 $63.00 $174.30 $374 $1,742 $337,763 $5,487 $65,138 COMPANY 1 2 3 4 5 1 2 3 4 5 Amedica Corp Aurora Spine Dynatronics Corp Alphatec Holdings Xtant Medical Hldgs SYMBOL AMDA ASG.V DYNT ATEC XTNT PRICE $0.53 $0.12 $3.04 $2.79 $5.90 MKT CAP $2 $5 $25 $76 $78 AMDA MDXG LBL.V NVRO ATEC 853 GMED SPNE PCRX IART $0.53 $3.37 $0.05 $57.77 $2.79 $1.19 $52.02 $12.83 $36.40 $63.00 MKT CAP 30-DAY CHG $2 $374 $4 $1,732 $76 $1,742 $5,055 $187 $1,483 $5,487 -51.95% -38.73% -34.01% -29.63% -18.90% -9.75% -6.81% -6.76% -5.08% -4.75% PEG 1.14 1.40 2.54 2.73 2.92 SYMBOL RTI Surgical CryoLife MicroPort Scientific NuVasive ConMed RTIX CRY 853 NUVA CNMD PRICE $4.70 $29.65 $1.19 $53.89 $73.78 MKT CAP P/E $298 $1,086 $1,742 $2,762 $2,069 117.50 94.34 92.53 56.70 48.28 HIGHEST P/E TO GROWTH RATIO ( EARNINGS ESTIMATES ) COMPANY 1 2 3 4 5 LOWEST PRICE TO SALES RATIO (TTM) COMPANY Amedica Corp MiMedx Group Lattice Biologics Nevro Corp Alphatec Holdings MicroPort Scientific Globus Medical SeaSpine Hldgs Corp Pacira Integra LifeSciences PRICE HIGHEST PRICE / EARNINGS RATIO (TTM) LOWEST P/E TO GROWTH RATIO ( EARNINGS ESTIMATES ) COMPANY SYMBOL SYMBOL RTI Surgical Smith & Nephew Orthofix ConMed NuVasive RTIX SNN OFIX CNMD NUVA PRICE MKT CAP PEG $4.70 $36.01 $58.10 $73.78 $53.89 $298 $15,746 $1,096 $2,069 $2,762 7.83 4.77 4.56 4.02 4.00 HIGHEST PRICE TO SALES RATIO (TTM) PSR 0.21 0.63 0.69 0.75 0.94 COMPANY 1 2 3 4 5 SYMBOL Flexion Therapeutics TiGenix AxoGen Globus Medical CryoLife FLXN TIG.BR AXGN GMED CRY PRICE $26.99 $2.07 $52.75 $52.02 $29.65 MKT CAP $1,016 $614 $2,011 $5,055 $1,086 PSR: Aggregate current market capitalization divided by aggregate sales and the calculation excluded the companies for which sales figures are not available. ryortho.com | 1-888-352-1952 PSR 2861.46 677.53 33.28 7.95 5.73

Orthopedics This Week - 2018 | July 17, 2018 | Page 3