NTU Undergraduates' research April 2014 - Biosciences | Page 95

Identification of the Gamma-hydroxybutyrate (GHB) receptor

Abstract
Gamma-hydroxybutyric acid (GHB) is a metabolite of the primary inhibitory
neurotransmitter in the brain, GABA. The first step of this pathway occurs when GABA is
catabolized to form succinic semialdehyde by the activity of GABA t &