MU Department of Medicine 2011-2013 Annual Report Feb. 2014

72 Annual Report University of Missouri- Columbia endocrinology cont. Obesity Society and The American Society of Hypertension. Obesity (Silver Spring) 21(1):8-24, 2013. Lastra G, Santos FR, Hooshmand P, Hooshmand P, Mugerfeld I, Aroor AR, Demarco VG, Sowers JR, Henriksen EJ. The novel angiotensin II receptor blocker azilsartan medoxomil ameliorates insulin resistance induced by chronic angiotensin II treatment in rat skeletal muscle. Cardiorenal Med 3(2):154-164, 2013. Laughlin MH, Davis MJ, Secher NH, van Lieshout JJ, Arce AA, Simmons GH, Bender SB, Padilla J, Bache RJ, Merkus D, Duncker DJ. Peripheral Circulation. Compr Physiol 2(1): 321-447, 2012. Ma L, Gul R, Habibi J, Yang M, Pulakat L, Whaley-Connell AT, Ferrario CM, Sowers JR. Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the transgenic (MRen2) rat. Am J Physiol Heart Circ Physiol 1;302(11):H2341-51, 2012. Mandavia CH, Aroor AR, Demarco VG, Sowers JR. Molecular and metabolic mechanisms of cardiac dysfunction in diabetes. Life Sci 92(11):601-8, 2013. Mandavia CH, Pulakat L, Demarco V, Sowers JR. Over-nutrition and metabolic cardiomyopathy. Metabolism 61(9):1205-10, 2012. Mandavia CH, Sowers JR. Phosphoprotein phosphatase PP2A regulation of insulin receptor substrate 1 and insulin metabolic signaling. Cardiorenal Med 2(4):308-313, 2012. Manrique C, Demarco VG, Aroor AR, Mugerfeld I, Garro M, Habibi J, Hayden MR, Sowers JR. Obesity and insulin resistance induce early development of diastolic dysfunction in young female mice fed a Western diet. Endocrinology 154(10):3632-42, 2013. Manrique C, Lastra G, Habibi J, Mugerfeld I, Garro M, Sowers JR. Loss of estrogen receptor signaling leads to insulin resistance and obesity in young and adult female mice. Cardiorenal Med 2(3):200-210, 2012. Manrique C, Lastra G, Habibi J, Pulakat L, Schneider R, Durante W, Tilmon R, Rehmer J, Hayden MR, Ferrario CM, Whaley-Connell A, Sowers JR. Nebivolol improves insulin sensitivity in the TGR(Ren2)27 rat. Metabolism 60(12):1757-66, 2011. Martin JS, Padilla J, Jenkins NT, Crissey JM, Bender SB, Rector RS, Thyfault JP, Laughlin MH. Functional adaptations in the skeletal muscle microvasculature to endurance and interval sprint training in the type 2 diabetic OLETF rat. J Appl Physiol 113(8): 12231232, 2012. McCurley A, Pires PW, Bender SB, Aronovitz M, Zhao MJ, Metzger D, Chambon P, Hill MA, Dorrance AM, Mendelsohn ME, Jaffe IZ. Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nat Med 18(9): 1429-1433, 2012. McFarlane SI, McCullough PA, Sowers JR, Soe K, Chen SC, Li S, Vassalotti JA, Stevens LA, Salifu MO, Kurella Tamura M, Bomback AS, Norris KC, Collins AJ, Bakris GL, Whaley-Connell AT; KEEP Steering Committee. Comparison of the CKD epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD) study equations: prevalence of and risk factors for diabetes mellitus in CKD in the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis 57(3 Suppl 2):S24-31, 2011. Muniyappa R, Sowers JR. Endothelial insulin and IGF-1 receptors: when yes means NO. Diabetes 61(9):2225-2227, 2012. Muniyappa R, Sowers JR. Role of insulin resistance in endothelial dysfunction. Rev Endocr Metab Disord 14(1):5-12, 2013. Nistala R, Andresen BT, Pulakat L, Meuth A, Sinak C, Mandavia C, Thekkumkara T, Speth RC, Whaley-Connell A, Sowers JR. Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket. Am J Physiol Renal Physiol 304(8):F1105-13, 2013. Nistala R, Hayden MR, Demarco VG, Henriksen EJ, Lackland DT, Sowers JR. Prenatal programming and epigenetics in the genesis of the cardiorenal syndrome. Cardiorenal Med 1(4):243-254, 2011. Nistala R, Sowers JR. Hypertension: Synergy of antihypertensives in elderly patients with CKD. Nat Rev Nephrol 9(1):13-5, 2013. Nistala R, Sowers JR, Whaley-Connell A. Over-nutrition contributes to tubulointerstitial fibrosis by targeting nutrientsensing kinases: Role for the mTOR/S6K pathway. Cell Cycle 11(5):831-2, 2012. Oberlin DJ, Mikus CR, Kearney ML, Hinton PS, Manrique C, Leidy HJ, Kanaley JA, Scott Rector R, Thyfault JP. One Bout of Exercise Alters Free-Living Postprandial Glycemia in Type 2 Diabetes. Med Sci Sports Exerc, 2013 Jul 18. Ofili EO, Oparil S, Giles T, Pitt B, Purkayastha D, Hilkert R, Samuel R, Sowers JR. Moderate versus intensive treatment of hypertension using amlodipine/valsartan and with the addition of hydrochlorothiazide for patients uncontrolled on angiotensin receptor blocker monotherapy: results in racial/ethnic subgroups. J Am Soc Hypertens 5(4):249-58, 2011. Ofili EO, Zappe DH, Purkayastha D, Samuel R, Sowers JR. Antihypertensive and metabolic effects of angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive african american and white patients. Am J Ther 2091):2-12, 2012. Oparil S, Giles T, Ofili EO, Pitt B, Seifu Y, Hilkert R, Samuel R, Sowers JR. Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on

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