MU Department of Medicine 2011-2013 Annual Report Feb. 2014 | Page 54

54 Annual Report University of Missouri- Columbia funded research Cardiovascular Medicine Kevin Dellsperger, MD, PhD Co-Investigator Co-Principal Investigator Coordinator of A 104 week, Mechanisms of Reperfusion-Induced randomized, double-blind, placebo- Kul Aggarwal, MD Endothelial Dysfunction, National controlled, parallel-group, multicenter Principal Investigator Institutes of Health, $250,000; study to evaluate the efficacy of PEGASUS TIMI-54 Study, $126,000, 10/01/2011 to 03/31/2012 aliskiren on the progression of atherosclerosis in patients with 01/01/2011 to 12/31/2011 Co-Principal Investigator coronary artery disease when added Principal Investigator Role of Cytokine-Induced Inflammation to optimal background therapy, Thrombin Receptor Antagonist to in Endothelial Dysfunction in AQUARIUS, $151,000, 12/08/2008 to Reduce Events in Acute Coronary Diabetes, National Institutes of Health, 12/31/2013 Syndrome, TRACER, $186,000, $250,000, 10/01/2011 to 12/31/2012 William Fay, MD 06/24/2009 to 12/05/2012 Mary Dohrmann, MD Principal Investigator Principal Investigator Principal Investigator Roles of Plasminogen Activator Thrombin Receptor Antagonist Permanent Atrial Fibrillation Outcome Inhibitor-1 and Vitronectin in Failure of for Secondary Prevention of Study Using Dronederone on Top of Coronary Revascularization, National Atherothrombotic Events, TRA2P/ Standard Therapy, PALLAS, $13,5000, Institutes of Health (R01), $250,000, TIMI-50, $150,610, 03/01/2008 to 09/20/2010 to 10/12/2012 09/01/2010 to 8/31/2014 12/14/2012 Greg Flaker, MD Co-Investigator Principal Investigator Co-Investigator Thrombosis and Hemostasis in Host Improved Reduction of Outcomes: Apixaban for Reduction in Stroke and Defense from Bacterial Infection, VYTORIN Efficacy International Trial. Other Thromboembolic Events in NIH/NHLBI Program Project Grant, Simvastatin Vs Vytorin in Acute Atrial Fibrillation, Aristotle, $332,688, $223,863, 04/01/2009 to 03/31/2014 Coronary Syndromes, IMPROVE-IT 08/01/2007 to 10/28/2013 Co-Investigator Study, $225,750, 03/02/2006 to 09/01/2020 Primary Investigator Improved long-term biocompatibility A Placebo-Controlled, Double Blind, of coronary stents by plasma coating Principal Investigator Randomized, Multi-Center Study to process, National Institutes of Health Prevention with Ticagrelor of Assess the Effects of Dronedarone (R44), $282,614, 09/01/2011 to Secondary Thrombotic Events in High- 400mg bid on Atrial Fibrillation 02/28/2014 Risk Patients with Prior Acute Coronary Burden in Subjects with Permanent Syndrome, PEGASUS-TIMI-54 Study, Atrial Fibrillation, HESTIA, $26,800, Co-Investigator $126,000, 02/14/2011 to 02/13/2016 07/23/2010 to 11/19/2012 Prevention of Vein Graft Intimal Hyperplasia with Human Apyrase, Principal Investigator Co-Investigator National Institutes of Health (R44), Randomized Evaluation of the Permanent Atrial Fibrillation Outcome $281,598, 10/01/2012 to 09/30/2013 Effects of Anacetrapib through Lipid- Study Using Dronederone on Top of Modification, REVEAL TIMI-55 Trial, Standard Therapy, PALLAS, Sanofi- Primary Investigator $25,612, 03/07/2012 to 03/06/2017 Aventis, $97,140, 09/20/2010 to Targeting Plasminogen Activator 10/12/2012 Inhibitor-1 t