Mount Carmel Health Partners Clinical Guidelines Asthma | Page 3

Management Patient Education The goal of asthma management is to reduce functional impairment and risk. “Impairment” refers to the intensity and frequency of asthma symptoms and the degree to which the patient is limited by these symptoms. The goal is to: • Prevent frequent or troublesome symptoms • Maintain activities indicative of normal daily living • Minimize the need (less than or equal to 2 times per weeks) of inhaled short-acting beta agonists (SABAs) to relieve symptoms • Lessen nighttime awakenings (less than 2 nights per month) • Optimize lung function • Reduce risk • Prevent recurrent exacerbations and the need for emergency department or hospital care • Prevent reduced lung maturation in children • Prevent the loss of lung function in adults • Optimize pharmacology with minimal or no adverse side effects • Teach patient how to manage and control asthma signs/symptoms. • Provide medication instructions. • Reinforce the importance of compliance. • Demonstrate proper inhaler usage. • Instruct patient on spacer/holding chamber usage. • Discuss self-monitoring skills and the avoidance of triggers. Vaccinations • Influenza vaccination: the live attenuated vaccine (nasal spray) is not recommended for people with asthma; the inactivated vaccine (flu shot) should be given. • Pneumococcal vaccination: recommended for all adults with asthma. For persons ages 65 and older, a one-time revaccination is recommended if previously vaccinated five or more years earlier and less than age 65 at the time of primary vaccination. Indicators for Referral • The patient has required hospitalization or more than 2 bouts of oral corticosteroids in a year • A diagnosis of asthma is uncertain • The patient has asthma that is difficult to control • Patient suffers frequent or continuous exacerbations • The adult or pediatric patient older than age 5 requires Step 4 care or higher or a child under age 5 requires Step 3 care or higher Ongoing Monitoring Routine follow-up after establishing the diagnosis of asthma should be scheduled within one month of the initial evaluation. Subsequent visits should be scheduled every one to six months depending upon the severity of the asthma. Follow-up visits are recommended within two weeks of an emergency room visit or inpatient admission. Consult a pulmonologist, asthma specialist, or allergist depending upon the patient’s condition. Inhaled Steroids Generic Name (Brand Name) albuterol (ProAir®, Proventil®, Ventolin®) Concentration (mcg/puff) levalbuterol (Xopenex®) 45 Short-Acting Anticholinergic ipratropium (Atrovent®) 17 Combined Short-Acting Beta Agonist and Short-Acting Anticholinergic ipratropium/Albuterol (Combivent®) 20/100 beclomethasone (Qvar®) 40, 80 budesonide (Pulmicort®) 90, 180 Category Category 90 Short-Acting Beta Agonists Inhaled Corticosteroids fluticasone propionate (Flovent®) fluticasone furoate (Arnuity Ellipta®) mometasone (Asmanex®) Combination Long-Acting Beta Agonist and Inhaled Corticosteroid 44, 110, 220 Long-Acting Anticholinergic Generic Name (Brand Name) budesonide/formoterol (Symbicort®) fluticasone/vilanterol (Breo Ellipta®) Concentration (mcg/ puff) 80/4.5 160/4.5 Advair HFA 45/21 115/21 230/21 Advair Diskus 100/50 250/50 500/50 100/25 200/25 mometasone/formoterol (Dulera®) 100/5 200/5 tiotropium (Spiriva Respimat® ONLY) 1.25, 2.5 fluticasone/salmeterol (Advair®) 100, 200 100, 200 Black Box Warning--Asthma-Related Death: fluticasone/sameterol (Advair®), fluticasone/vilanterol (Breo Elipta®), budesonide/formoterol (Symbicort®), mometasone/formoterol (Dulera®) Long-acting beta-2 adrenergic agonists (LABA) increase the risk of asthma-related death. Data from a large placebo-controlled U.S. study showed an increase in asthma-related deaths in patients receiving salmeterol plus a usual asthma treatment, with results considered to be a LABA class effect. There is inadequate data to determine if concurrent inhaled corticosteroids or other long-term asthma control treatments mitigate an increased risk of asthma-related death from LABA. LABA use may increase the risk of asthma-related hospitalization in pediatric and adolescent patients. Use only for asth ma patients not controlled on long-term asthma control treatment such as an inhaled corticosteroid or whose disease severity requires treatment with both corticosteroid and LABA. Once asthma control is achieved and maintained, assess the patient at regular intervals and initiate a step down treatment (such as discontinue corticosteroid/LABA combination) if possible without loss of asthma control. Maintain the patient on a long-term asthma control treatment such as inhaled corticosteroid; do not use corticosteroid/ LABA combination if asthma is adequately controlled on low-or medium-dose inhaled corticosteroids. Asthma - 3