MMRF Accelerator Magazine Summer 2015 Edition | Page 4

The MMRF Precision Medicine Model The MMRF actively drives drug discovery and development with a unique model that has proven results. It is comprised of three interrelated parts. THE DATA BANK Data generation & integration THE LEARNING NETWORK Collaboration and discovery THE CLINIC Accelerating trials MMGI Gateways MMRC CoMMpass Myeloma Disease Model - Molecularly targeted therapies Registry Translational Network - Immune therapies - Novel therapies The Data Bank An unprecedented collection The Learning Network The Clinic  Collaboration that focuses  A network of best-in-class partners of high-quality patient upon access to new targets launching clinical trials 60% faster molecular and clinical data. and drugs to advance than average. trials faster than any other organization. The Data Bank of 500 relapsed/refractory patients progresses over at least 8 years for In 2005, the MMRF established the first to obtain “blueprints” of particular each patient. This will create the largest, comprehensive tissue banking effort forms of myeloma and help identify most comprehensive catalog of multiple in multiple myeloma. It has accessed treatment options. In July 2011, the myeloma genomic and clinical data, over 4,000 patient samples and clinical MMRF CoMMpass Study began and enable physicians to match specific data from newly diagnosed and collecting clinical information and treatment approaches to the patients relapsed patients. sequencing myeloma cells from patients’ most likely