A QUICK GLANCE AT WHAT WE’ RE WORKING ON …
DIABETES
Diabetic nephropathy is a common complication of diabetes and the leading cause of end stage renal failure that has affected two million people worldwide. Monash researchers are running clinical trials to study the effects of tocotrienol-rich vitamin E with results showing improved kidney function in patients, even up to nine months after the doses were stopped – a promising treatment to delay the progression of this serious disease.
CURCUMIN ANALOGS
Recent research suggests that curcumin, a bioactive compound extracted from turmeric, shows promising potential in cancer treatment. Its analogs and derivatives possess enhanced physicochemical and biological properties and exhibit improved stability and potency, thereby enhancing curcumin’ s overall therapeutic efficacy. Using colorectal, lung, breast, cervical, and prostate cancer cell lines as experimental models, we aim to elucidate the molecular mechanisms underlying its anticancer effects. The findings are expected to contribute to the future development of novel anticancer drugs.
SNAKE VENOM
Snake venom consists of a complex mixture of several toxic proteins and enzymes with a wide spectrum of biological activities that may have anticancer properties. Our researchers are isolating and testing proteins in the venom of the Malaysian arboreal viper for the cytotoxic activity and growth inhibition of malignant cancer cells, providing clues for the development of anti-cancer drugs.
EMERGING INFECTIOUS DISEASES
The ongoing emergence of infectious diseases over the past century has revealed a lack of global preparedness in preventing or responding to future outbreaks. Our researchers are decoding the interactions between host cellular factors and viruses, particularly vector-borne diseases like dengue, Zika, chikungunya, and others with pandemic potential such as influenza and enteroviruses, with a focus on developing new treatments and vaccines.
WHAT DOES INCLUSIVE HEALTHCARE REALLY LOOK LIKE?
Professor Umadevi Palanisamy shares her mission to create equal access and empower differently-abled communities through medical innovation. SCAN TO WATCH
23