Medical Chronicle November/December 2013 | Page 22

CARDIAC PROF JAMES KER Consulting Editor Systolic blood pressure control About 54% of the stroke burden and 47% of ischaemic heart disease burden worldwide is attributable to high blood pressure. These figures give a glimpse of the large impact that elevated blood pressure has on mortality and morbidity. Systolic hypertension is more common than diastolic hypertension and systolic blood pressure contributes more of this global burden of disease than diastolic blood pressure. The blood pressure profiles change as people age in such a way that up to 75% of people with high blood pressure are above the age of 50 years and the main cause for the elevated blood pressure is systolic blood pressure. Above the age of 50, blood pressure is all about systolic pressure. Furthermore, with increasing age, as the systolic blood pressure rises, the diastolic blood pressure tends to flatten out and may even start to lower so that the pulse pressure increases. This condition that became recognised as isolated systolic hypertension is caused mainly by an increased stiffness of the arteries due to a reduction of compliance and reduced elasticity of the blood vessels, which includes the aorta 2vV???F?R7F?ffV?VB'FW&?W26??G&?'WFRF??V?WfF?????F?P?&WGW&???r&Vf?V7FVB'FW&??&W77W&P?vfRg&??F?RW&??W'??W?FV????v?2FF?W?FV????v?2FF?b??V??P?6??vVBF?BV??Rv?F???vW"&???@?&W77W&R?WfV?2?WfV?2??r2?7?7F??2&W77W&R?bV??r??fP?F?R?V7B?V?&W"?b6&F??f67V? ?WfV?G2?F?W&R?2??V"&V?F???6???&WGvVV?&?6??r&???B&W77W&R?WfV?0??B6&F??f67V?"WfV?G2?W6??rF??0?W?FV????v?2FF??B?2??B?76?&?P?F?&VF?7Bv?Bv?V?B?V??`?&???B&W77W&R?WfV?2&R&VGV6VB'???&?6???v?2G'Vw2F?6???"??p??WfV?2???f7B?67V?V?FVBFF?fP?7VvvW7FVBF?BW?6W76?fR??vW&??r?`?&???B&W77W&R'?G'Vw2????7&V6P?6&F??f67V?"WfV?G2?"?fR???FF?F????&VGV7F????bF?W6RWfV?G2??'WBF?B7G&??R&?6???WfV?gW'F?W ?&R&VGV6VB'?F?W6R??r?WfV?2?G&VF?V?BVffV7@?&Wf??W6??FF?'F??VBg&??G'VP?7F?fRG'Vrg2G'VR?6V&?G&VF?V?@??fR6??v??g&??FF?'F??VBg&???cR???"??CrccrF?V?G2G&VFV@?f?"B???V'2?6?v??f?6?F?&VGV6V@????"6&F??f67V?"WfV?G2?F?W&P??v23?R&V?F?fR&?6?&VGV7F????`?3?R??RR4??3R?CRR??b7G&??R??F?W&Rv2&V?F?fR&?6?&VGV7F????`?bR??6?&??'??V'BF?6V6R??RR4????R?#2R??B&V?F?fR&?6?&VGV7F?????b#R?????f67V?"FVF?2??F?W6RF?V?G2???B7?7F??2&???@?&W77W&R?b?c??r?vR?F?W&Vf?&R??F???B?fRV??Vv?FF??F?P?G&VF?V?BVffV7B??V??Rv?F?&???@?&W77W&W2?b?c??r??F?R5?5B?UU"G&???F?V?G2vW&P?Wf?VFVBf?"F?RG&VF?V?BVffV7@????6??FVB7?7F??2??W'FV?6??????Cc?RF?V?G2v?F??V?vR?bs??V'2?fW"Gv??V'2?bG&VF?V?B??7F?fRG&VF?V?B&VGV6VBF?R&FR?`?7G&??Rg&??2?r?F?V?B?V'0?F?r???F?V?B?V'2?&V?F?fP?&?6?&VGV7F????bC"R???2?@?6&F?2V?G???G2FV6??VB'?#bR????2???FW"?WF???6?2?bV?v?BG&??0????RF?V?G2G&VFVBf?"2??V'26??vVB&VGV7F???????'F?G???b2R??RR4??"?#"R??&VGV7F?????7G&??R?b3R?B6&F??f67V? ?WfV?G2?b#bR?F?R?V?&W"F??G&VB?fW"f?fR?V'2F?&WfV?B??P?6&F??f67V?"WfV?Bv2?f?"?V???B3?f?"v??V???WrG&??FF??V?FW&?F?V?G0??F?R&W6V?BFF&R&6VB??F?P?f??F??r6&F??f67V?"WfV?G0?F?&?Vv?6??&??F???F?W&????F?V?G2?f??rv?F?7?7F??0???W'FV?6????44???4??G&????F??2v2&W7V6?f?VB7V&w&?W???6?2?bF?R?&?v???G&???F?P???v2F?W???&RF?R&V?F???6???&WGvVV?6???6??WF6??W2?@?F?ffW&V?B?WfV?2?b7?7F??2&???@?&W77W&R??sRF?V?G2?b??v??&?6????W'FV?6?????F?W?vW&RF?f?FVB??F?f?W"w&?W0?&6VB??F?V?"7?7F??2&???B&W77W&S???C??r?3F??C??r??#F??3??r?BF???#??r?F?R&??'?V?G???@?v26&F??f67V?"FVF??????fF????6&F????f&7F????"7G&??R?F?W6P??WF6??W2vW&R6??&VB&WGvVV?F?P?F?ffW&V?B&???B&W77W&Rw&?W2???F??6RÃ?V'2??Bv?F?7?7F??2&???B&W77W&R?b?c??r?6??V?@??fRF?V?"&???B&W77W&R&VGV6VBF?CF??S??r?&W7V?G0???Ur$???B$U55U$Rt??2??uT?DT??P???F?R&V6V?F?V&?6?VBWW&?V?wV?FV??W2?F?Rv??&???B&W77W&Rv0?FVf??VB3???7?7F??2&???B&W77W&R?C??p?????F?V?G2?b??r???FW&FR6&F??f67V?"&?6??"??F?V?G2v?F?F?&WFW2?V??GW0?2??6??V?B&R6??6?FW&VB??F?V?G2v?F?&Wf??W2G&?6?V?B?66?V?0?GF6??"7G&??P?B??6??V?B&R6??6?FW&VB??F?&WF?2?B????F?&WF?2F?V?G2v?F?6?&???0???F?W?F?6V6R?"??F??6RÃ?V'2?bvRv??&Rf?B6?V?B?fRF?V?"&W77W&R&VGV6VBF???C??rFFVBF?F??W&&??G???2??F??6R???V'2??B?7?7F??2&???B&W77W&R6??V?B&R?S??r???@???vW"F??C??bF?W?&R??v??B??6?6??B?V?F?6??F?F????F?7F??2&???B&W77W&P???F?7F??2&???B&W77W&RÓ??rf?"????"??F?7F??2&???B&W77W&R??V??rf?"F?&WF?72?26fR?BvV???F??W&FVB?6??6?W6????7?7F??2&???B&W77W&R??26?v??f?6?B&??R??F??6R??FW"F??S??V'2?6?v??f?6?B&VGV7F???2??6&F??f67V?"WfV?G26?&R6??WfV@?'?6??G&????r7?7F??2&???B&W77W&R??WrwV?FV??W2&?f?FR6WB?`?F?ffW&V?B7?7F??2&???B&W77W&W2f?"F?ffW&V?B6??F?F???2?#"?TD?4?4?$???4?R??dT?$U"?DT4T?$U"#0??F?R&??'?V?G???B?67W'&VB??RP??bF?V?G2v?F?%?C??r0?6??&VBF??C??r?r?bR??&?6??&VGV7F???3?R??RR4??#2?SR??F??6P?v?F?%?b?#??rg2?3??p??B6?v??f?6?B&VGV7F?????7G&??R?'W@????7&V6R????6&F????f&7F????6??6?W6????6&F??f67V?"WfV?G2vW&P?6?v??f?6?F???vW"??F??6Rv?F??&???B&W77W&R?WfV?2?C?@??3??r?'WB&???B&W77W&P??WfV?2?#??r???&VGV6V@?7G&??R?'WB??7&V6VB??6&F?????f&7F?????&VfW&V?6W2f??&?R??&WVW7B?