Market World Active Pharmaceutical Ingredients Market | Page 2

Synthesis Type Insights
Based on synthesis type, the market is categorized into synthetic and biotech. Various methods are adopted by
the manufacturing companies depending up on the complexity of the molecule required. Synthetic drugs are
manufactured on the basis of organic chemistry in contrast to biotechnology based drugs, which are produced
by utilizing molecular techniques. Further classification of biotech segment is recombinant proteins, monoclonal
antibodies and vaccines.
In 2015, synthetic segment held the largest share. The key factors for the biotech APIs segment growth are large
R&D investment for new biosimilars, increasing demand for protein-based medicines, and rising focus of key
manufacturers toward biological drugs.
Manufacturer Type Insights
Based on the type of manufacturer, it is categorized into outsourced or merchant or in-house or captive APIs.
According to market estimates, in 2015, in-house APIs was the largest segment and outsourced APIs are
anticipated to be the fastest growing market.
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All pharmaceutical companies does not have separate unit for the formulation of API. This has led to rise in the
outsourcing of the molecules from the production sites. The need of investment in expensive production
processes is eliminated by the outsourcing.
Type Insights
Based on the type, APIs are classified into innovative and generics. Branded products come under innovative
type, whereas the generic drugs are the ones, which are available OTC (over the counter). Owing of high rate of
prescription, high drug development initiatives, and high price, the innovative APIs segment dominated in 2015.
Generic segment is anticipated to be fastest-growing type, due to expirations of patents of various blockbuster
drugs. Patent expirations of branded drugs have very serious negative impacts on the drug producers, as the
companies face the tremendous loss after expiration. Hence the drug manufacturers prefer more generic drugs
than the branded ones.