In 2001 , the US Food and Drug Administration ( FDA ) approved Tracleer as the treatment for patients with PAH . Actelion develop the Tracleer and the sales of Tracleer grew rapidly due to a high patient switch over from off-label drugs to Tracleer . Tracleer , the major revenue generating drug of the PAH market is expected to go off patent by 2015 .
Despite an increase in per-member-per-year spend from 2013 to 2014 ; trend for medications used to treat pulmonary hypertension is expected to be sluggish again in 2015 , chiefly because of the market saturation of generic sildenafil . The global PAH market is expected to achieve highest sales till now in the year 2017 due to imminent release of the PAH drug called Uptravi ( Selexipag ) in 2016 , which is anticipated to potentially drive the growth of the total market till 2019 . Popularity of combinational therapies is also likely to drive the market in the aforementioned period .
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Some points from TOC : 1 . Executive Summary
2 . Pulmonary Arterial Hypertension ( PAH ): An Introduction 2.1 Definition of PAH 2.2 Classification of PAH 2.3 Causes of PAH 2.4 Who gets PAH ? 2.5 How Serious is PAH ? 2.6 Symptoms of PAH 2.7 Diagnosis of PAH 2.8 Treatment of PAH 2.8.1 Medications 2.8.2 Surgery 2.8.3 Lifestyle Changes 2.9 How does it affect ?
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