Description
The global market for RNAi technology is estimated to be USD 8.7 billion in 2014 and is expected to reach USD21.9 billion by 2019 , growing at a CAGR of 20.19 %
RNA interference ( RNAi ) is a natural process of treating forms of cancer and other diseases by posttranscriptional silencing of genes by small fragments of the nucleic acid . However , the path of RNAi therapies to the clinic has been more like a roller-coaster ride . RNAi technology can be helpful in providing target specificity to the proteins that lack the enzymatic pocket necessary for binding . Global RNAi Technology Market-Market Dynamics
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The major drivers for the growth of the market are improving synthetic delivery carriers and chemical modifications to RNA , increasing genetic and metabolic disorders including diseases like cancer and increasing applications in molecular diagnostics , particularly that of cancer . However , the market is facing major challenges because of strict FDA regulations and the fact that RNA is potentially immunogenic and inherently unstable , which causes major problems for the research and development of drugs . Greatly expanding the number of druggable disease targets and potentially streamlining drug development are the market growth opportunities in the coming years .
RNAi technology is showing promise in the treatment of viral infections like hepatitis B virus ( HBV ), which affects more than 300 million worldwide , killing at least 780,000 annually through liver scarring , liver failure , and liver cancer . There has been a shift in strategic focus of RNAi innovators from RNAi triggers to delivery . Small RNAi therapeutics innovator ( pure-play ) companies and Big Pharma remain the industry ' s two protagonists , although medium-sized pharmaceutical companies , including those in Asian countries , have taken some of the space vacated by Big Pharma . RNAi technology has application in different sectors like drug discovery and development and therapeutics . Therapeutics is the major growing sector owing to the increased demand for treatment of cancer and liver disorders .
The market is segmented by type of application ( drug discovery and development , therapeutics , and others ), by therapeutics ( oncology , ocular disorders , respiratory disorders , liver diseases , and neuronal disorders ) and geography ( North America , Europe , and Asia-Pacific ).
The key players in the market are focused on the expansion of their business by launching new products and extending the product line . Mergers and acquisitions of small and medium-sized manufacturers to enter the overseas market is another strategy adopted by multinational players . RNAi technologies market is still at their nascent stage but companies are keen on taking this market to a higher level .
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Some of the key players in the market are : Alnylam Pharmaceuticals www . orbisresearch . com ; + 1 ( 214 ) 884-6817 ; + 9120-64101019