3.3.1 U . S . FDA 3.3.2 Europe CE mark 3.3.3 Others 3.4 Reimbursement scenarios 3.5 Clinical trials 3.6 Patent analysis 3.6.1 Patent analysis , by year 3.6.2 Patent analysis , by company 3.7 Top impacting factors 3.7.1 Drivers 3.7.1.1 Rise in the prevalence of chronic illnesses 3.7.1.2 Technological advancements 3.7.1.3 Short duration and high efficacy of the procedure 3.7.2 Restraints 3.7.2.1 Government regulations and reimbursement policies 3.7.2.2 High cost and limited awareness 3.7.3 Opportunities 3.7.3.1 Increase in the level of awareness 3.7.3.2 Untapped markets in emerging economies
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