Whole Exome Sequencing Market
Publication Month: Aug 2019 | Report Code: TIPRE00005519 | No. of Pages:
178 | Category: Biotechnology | Status: Published
Reduction in Time and Cost for Sequencing
The exon is part of a genome which is responsible for making 1 or 2 percent of the entire genome of a
person. All of the exon in a genome are together known as the exome. And thus, sequencing is of these
is known as whole-exome sequencing. The whole-exome sequencing allows identifying the variations in
the protein-coding sites of any gene compared to sequencing a few genes together. The whole-exome
sequencing is preferred widely due to its property to identify a mutation in a single exon. Identifying
mutation in at the original site makes whole-exome sequencing an efficient method and enable to
identify possible disease-causing mutation.
The advancement in the field of genomics has led to a significant reduction in the time and cost of
genome sequencing. The related cost of sequencing with different sequencing techniques and
strategies are of interest as they influence the scope and scale of the genomic research studies. Thus,
it makes whole-exome sequencing much-preferred method than whole-genome sequencing.
The advantages of exome sequencing have resulted in the reduction of time and cost to a great extent.
Approximately 2% of the genome is sequenced by the WES method; however, it generally sequences the
exon at a deeper level it sequence to 100X. The technique enables sequencing through a process
where the DNA and RNA are hybridized with the protein-coding site and is isolated from the non-coding
site. Also, the data required for 100X sequencing is approximately 5- 6GB, whereas, in genome
sequencing, it is nearly 90GB. Thus, these factors offer lower data storage, faster, cheaper, and more
accessible data analysis. Therefore, owing to the above-mentioned factors, it is estimated that the
market for whole-exome sequencing is likely to grow significantly during the forecast period.
E-Mail : [email protected]