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Each cell comprises of DNA packed with numerous individual genes that have a set of instructions to guide each cell on its function, division and growth. In the event that there are errors in these instructions, the cell will stop its normal functioning and it will become cancerous growing at an abnormal rate. So, what causes the changes in the DNA of the cells? Even though the real causes of cancer remain unknown, we have several risk factors that increase the chances of contracting the deadly disease. Some of these risk factors include the use of tobacco, bad alcohol habits, exposure to harmful environment carcinogens, infectious ailments like HIV/AIDS, Human Papilloma Virus (HPV ), and Hepatitis B & C, bacterial infections as well as parasitic infestations. Risk Factors While doctors have an idea of what may increase your risk of cancer, the majority of cancers occur in people who don't have any known risk factors. Factors known to increase your risk of cancer include Your age: Cancer can take decades to develop. That's why most people diagnosed with cancer are 65 or older. While it's more common in older adults, cancer isn't exclusively an adult disease - cancer can be diagnosed at any age. This is why the call for regular screening cannot be over- emphasized, given that the earlier you diagnose the disease, the higher your chances for getting cured are. Your habits: Certain lifestyle choices are known to increase your risk of cancer. Smoking, drinking more than one alcoholic drink a day (for women of all ages and men older than age 65) or two drinks a day (for men age 65 and younger), excessive exposure to the sun or frequent blistering sunburns, being obese, and having unsafe sex can contribute to cancer. You can change these habits to lower your risk of cancer - though some habits are easier to change than others. Your family history: Only a small portion of cancers are due to an inherited condition. If cancer is common in your family, it's possible that mutations are being passed from one generation to the next. You might be a candidate for genetic testing to see whether you have inherited mutations that might increase your risk of certain cancers. Keep in mind that having an inherited genetic mutation doesn't 38 MAL31/19 ISSUE In 2015, The Daily Nation reported that the rate of death from cancer in Kenya is far outpacing population growth and may double by 2026! The report contin- ued that “cancer is now the third leading cause of death in Kenya and is threat- ening to move further up the list of top killers in the coming decade”. necessarily mean you'll get cancer. Your health conditions: Some chronic health conditions, such as ulcerative colitis, can markedly increase your risk of developing certain cancers. Talk to your doctor about your risk. Your environment: The environment around you may contain harmful chemicals that can increase your risk of cancer. Even if you don't smoke, you might inhale second hand smoke if you go where people are smoking or if you live with someone who smokes. Chemicals in your home or workplace, such as asbestos and benzene, also are associated with an increased risk of cancer. Complications Cancer and its treatment can cause several complications, including Pain: Pain can be caused by cancer or by cancer treatment, though not all cancer is painful. Medications and other approaches can effectively treat cancer-related pain. Fatigue: Fatigue in people with cancer has many causes, but it can often be managed. Fatigue associated with chemotherapy or radiation therapy treatments is common, but it's usually temporary. Difficulty breathing: Cancer or cancer treatment may cause a feeling of being short of breath. Treatments may bring relief. Nausea: Certain cancers and cancer treatments can cause nausea. Your doctor can sometimes predict if your treatment is likely to cause nausea. Medications and other treatments may help you prevent or decrease nausea. Diarrhea or constipation: Cancer and cancer treatment can affect your bowels and cause diarrhea or constipation. Weight loss: Cancer and cancer treatment may cause weight loss. Cancer steals food from normal cells and deprives them of nutrients. This is often not affected by how many calories or what kind of food is eaten; it's difficult to treat. In most cases, using artificial nutrition through tubes into the stomach or vein does not help change the weight loss. Chemical changes in your body: Cancer can upset the normal chemical balance in your body and increase your risk of serious complications. Signs and symptoms of chemical imbalances might include excessive thirst, frequent urination, constipation and confusion. Brain and nervous system problems: Cancer can press on nearby nerves and cause pain and loss of function of one part of your body. Cancer that involves the brain can cause headaches and stroke-like signs and symptoms, such as weakness on one side of your body. Unusual immune system reactions to cancer: In some cases, the body's immune system may react to the presence of cancer by attacking healthy cells. Called paraneoplastic syndrome, these very rare reactions can lead to a variety of signs and symptoms, such as difficulty walking and seizures. Cancer that spreads: As cancer advances, it may spread (metastasize) to other parts of the body. Where cancer spreads depend on the type of cancer. Cancer that returns: Cancer survivors have a risk of cancer recurrence. Some cancers are more likely to recur than others. Ask your doctor about what you can do