Louisville Medicine Volume 67, Issue 11 | Page 23

FROM HEAD TO TOE Fig. 4a Fig. 4b Fig. 4c unit principles, leaving flat, scarred, featureless lips and a life-long stigma. Dr. Millard carefully analyzed and measured the normal side aesthetics, and then transferred these features to the cleft side repair (fig. 4a). In doing so, he placed incisions along lines between lip aesthetic units, leaving less noticeable scars (fig. 4b, 4c). The im- proved results have now benefitted millions of children worldwide, reducing the stigma of this common condition. I had the pleasure of serving a fellowship with Dr. Millard, and subsequently applying the lessons learned as a volunteer surgeon with Operation Smile, a charitable organization whose teams travel worldwide to apply and teach cleft lip and related reconstructive procedures. I found the human and cultural lessons we learned in these and similar missions to be so inspiring as to be life-changing. In this manner, we benefitted differently, but as much as the children we served. cultures into large sheets the size of notebook paper, an important need for replacing skin of extensively burned patients. Key to the process was use of the recently discovered Epidermal Growth Factor, a protein that stimulates skin cell multiplication. The project was most successful. However, the number of patients here that were so extensively burned as to need this breakthrough were too few to justify the personnel and production costs. Now, commercial labs using a similar process serve burn units nationwide, and they have replaced local efforts such as ours. Shortly after his fellowship, Dr. Brown used his knowledge of growth factor biology to create cosmetic skin-care preparations. He founded a highly successful company, and a line of cosmetics, RéVive. Thus, his success in aesthetics came from a reconstructive foundation. RECONSTRUCTIVE PRINCIPLES APPLIED TO AESTHETIC USES Plastic surgery research is producing an expanding number of new techniques that involve fusion of aesthetic and reconstructive or wound biology principles to achieve better outcomes. These efforts will surely bring substantial benefits to tomorrow’s patients needing reconstruction or seeking aesthetic enhancements. A prime example of reconstruction serving aesthetics came from the UofL Surgery program. In the 1980s, I was asked by Hiram Polk, MD, to be a faculty mentor to a bright, energetic surgical graduate, Greg Brown, MD, who was appointed as fellow in the Price Institute of Surgical Research. Dr. Brown wished to establish a burn care program of growing postage-stamp sized skin biopsies in laboratory THE FUTURE Dr. Tobin is a professor at the University of Louisville School of Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery. He practices with UofL Physicians – Plastic and Reconstructive Surgery. Fig. 2 Legend to Figures Fig. 1 Aesthetic units of the upper lip and nose. Fig. 2 Aesthetic units of the full face. Fig. 3 Facial recognition algorithm patterns. Fig. 4 The Millard Rotation-Advancement cleft lip repair. a. Designing a repair pattern based on normal-side aesthetic features. b. Incising and moving the flaps of the repair. c. Finished repairs, with balanced, aesthetic form created. APRIL 2020 21