Louisville Medicine Volume 67, Issue 11 | Page 19

FROM HEAD TO TOE There is a continued pressure to be smart and either be youthful or look that way. Regardless, most patients I see just want to look more like the youthful person they once were. Since facial rejuvenation constitutes the majority of the rise of these procedures and naturally is a great part of our identity, let’s focus on what aging is doing to us and our faces, and what can we do about it. The aging process manifests itself in complex changes in all tissue types of the face including skin, fat, muscle, fascia and bone. Skin changes include dermal collagen thinning, elastin de- cline and pigmentary changes. The fat starts to thin secondary to redistribution from hormonal changes and dietary changes. The muscle becomes more prominent without the softening effect of the overlying fat and lastly, the facial skeleton resorbs and remod- els over time. The suspension ligaments attenuate from gravity and elastin decline. In some patients, the tissue becomes malpo- sitioned or ptotic. The expressive genetic effects of aging and en- vironmental stressors including psychological stress are current topics of discussion as well. By examining the underlying structural changes in the face, the clinician can create a long-term comprehensive plan to ad- dress immediate problems and develop strategies to prevent fu- ture problems. In aging patients, some present with malabsorptive problems for iron, B12, zinc and other nutrients, or present with early symptoms for hypothyroidism or Type 2 diabetes. These problems have to be addressed in any potential surgical or min- imally invasive candidate to minimize complications. Early in the aging process, patients start to lose volume in their cheeks or lips. A popular treatment option is what is called dermal fillers. The majority of these fillers are made of a basic substance in our body called hyaluronic acid. Depending on their processing and chem- istry, they will have different characteristics making some more suitable for subdermal placement versus placement in the deeper soft tissue of the face to substitute for the missing facial volume. The body resorbs this material over the course of a year for the most part. The use of autologous fat is a popular filling material and some of this material has a chance of surviving long term as a fat graft. The objective is to replace the volume without distortion of the area in repose or in animation. This is where knowledge of anatomy, depth perception and patience come together. For areas of the face that are affected by animation, there is an- other cosmetic modality. As facial skin and fat tissue is thinning, there is deepening of skin tension lines (expressive wrinkle lines), such as the glabella (frown lines), forehead lines and periorbit- al lines (crow’s feet). The treatment options may include what is known as muscle chemodenervation with agents such as Botox or a combination of chemodenervation and dermal fillers. Subtle and conservative treatment is often a wiser approach. The envelope of the face, of course, is the skin. It displays both the short and long-term effects of our nutrition and our lifestyles. The damage is expressed by scar deformities, pigment changes, adult acne and thinning of the skin to name a few. The funda- mental treatment plan must address nutrition and, if pertinent, smoking cessation. The treatment options start with a basic skin care program to promote turnover of the skin cells. This can be started with products that break the outer skin layer bonds such as Retin-A which promotes exfoliation and starts the dynamic process of skin and collagen growth. This usually gives a healthier appearance to the skin and can treat some of the skin damaged as a result of UV radiation. There are synthetic chemical acids such as trichloroacetic (TCA), or fruity acids such as glycolic acid, that denatures the outer skin layer. These agents are commonly used around the world to exfoliate the outer skin layer and more aggressively stimulate skin turnover. In areas in the world where lasers are not affordable, these agents are the mainstay of a skin treatment procedure known as a chemical peel. The contemporary treatment for stimulating healthier skin is laser ablation. The laser best known for this is the carbon dioxide laser, or CO2 laser. The target chromophore is the water in the skin cell, which is precisely ablated on the surface resulting in exfoliation of the outer layer, which stimulates skin production and increases the collagen in the dermis, resulting in a healthier appearance. There is a plethora of information on lasers to treat different pigmented lesions, but it is important to know that you are not ablating a skin cancer, which is why experience both with the skin lesion and the laser’s capa- bilities is critical. As the patient ages, more invasive surgical procedures are re- quired including elevation of the deeper fascial structures such as the superficial musculoaponeurotic system (SMAS). Face and necklift procedures in conjunction with volume replacement such as the patient’s own fat tissue, are the mainstay of treatment meth- ods to restore the more youthful features of the face. Often other restorative procedures are concomitantly performed on the eye- lids, brow, neck and skin. Unfortunately, these procedures do not halt the aging process, so you should expect a basic maintenance skin care program. At the end of the day, the boring habits of a healthy lifestyle including good nutrition (I think the plant-based diet approach and its sugar-reducing variants are compelling), exercise, low stress and sun protection go a long way in keeping the person you see in the mirror looking like the vibrant youthful person you are. Dr. Chariker is a practicing plastic and reconstructive surgeon specializing in cra- niofacial and hand surgery at the Kentucky Center for Cosmetic and Reconstructive Surgery. APRIL 2020 17