Louisville Medicine Volume 63, Issue 3 | Page 37

DOCTORS’ LOUNGE glycemic index (apple cider vinegar and the anti-starch-absorption/anti-adiposity effects of better gut microbiomes) can reduce the incidence of atherosclerotic dementia, which is deeply tied to habits of sedentary obesity. Even cancer research is involved. Dr Catherine Stanton at Teagasc in association with the University College, Cork has shown (in the lab, not in people) that using engineered probiotic strains to quadruple the gut-microbial production of conjugated linoleic acid – which has been shown also to reduce fatty liver injury – resulted in reducing the viability of colon cancer cells by 92 percent. Probiotic adjustment of gut flora has been hailed as treatment for various gut diseases. Initially we thought that regular dosing of any probiotic given in conjunction with antibiotic use would prevent Clostridium Difficile diarrhea/colitis; it turns out that Saccharomyces boulardii is the active agent, that more than 10 billion colony-forming units per dose are needed, and that it is useful in prevention more than for treatment. However, its use in the immune-suppressed patient can be associated with fungemia. Other preparations including the very popular multi-lactobacillus probiotics have failed to prevent C diff. Probiotic use is confusing because of the paucity of provable outcomes – aside from C diff prevention – based on the formulae of the various products; the need or not for refrigeration; the (sigh) vegan part (raging internet debate about whether certain commercial products actually do contain gluten or gelatin); and the packaging, as in, does it still keep active on the shelf if in a plastic bottle instead of glass or individual blister packs. Therefore it is possible to pay $60 for thirty doses of a fancy liquid, or $50 for various products designed for “Mood” or “Prostate” or of course, “Ultra,” since this is America and we must always have the 90 billion CFUs, not just 10. How can you eat what’s good for your gut germs? Buy no-antibiotic meat at the farmers’ markets – the one on Bardstown Rd at Speed is open year-rou