Louisville Medicine Volume 62, Issue 6 | Page 16

WILL TREATMENT OF HEPATITIS C CAUSE CONFLICT AMONG PHYSICIANS? Thomas James III, MD T here is dissension in the ranks of practicing physicians. Treatment of one disease—Hepatitis C—threatens to take resources from the management of other medical and surgical conditions. That sounds like a very brash statement, but it is one being openly discussed inside the beltway. Hepatitis C is the most common chronic blood borne infection in this country. CDC estimates that 3 ½ to 4 million Americans have chronic infection with this virus. But this estimate may be an underestimation. The US Preventive Services Task Force (USPSTF) in 2013 issued recommendations based upon Level B evidence that all adults born between 1945 and 1965 have a one-time screening for Hepatitis C (HCV), along with a screen for HIV. The USPSTF apparently feels that Baby Boomers lived an especially more hedonistic life style in their youth, to create greater risk than other age group segments. Right upon the heels of the USPSTF’s pronouncement, CMS issued coverage guidelines allowing coverage of a one-time screen for Hepatitis C in Medicare beneficiaries who meet one of these conditions (1.): 14 • Those at high risk because they have a current or past history of illicit injection drug use • Those who had a blood transfusion before 1992, or • Those born between 1945 and 1965 LOUISVILLE MEDICINE With greater screening the numbers of individuals identified as infected with HCV is likely to rise. At the same time that mass screening is occurring, treatments are being more effective, easier to administer, and associated with a more benign side-effect profile. The days of Pegylated interferon and ribavirin with 30-40 percent sustained viral remission (SVR) have become supplanted by all oral drug regiments with relatively higher to \