22
LMS Issue 2 | 2014
Immunology & Immuno Histo/Haema
Efficient High Quality Frozen Sectioning
T
hermo Scientific has just released
t he Cr yoSta r N X 50, a ne w
manual cryostat that offers scientists
improved functionality and ergonomics
to ensure efficient high quality frozen
sectioning. Sectioning temperature is
critical in generating a good quality
fresh frozen tissue section.
The CryoStar NX50 is an innovative
cryostat incorporating knife cooling
and adjustable specimen head temperature for rapid adjustment to meet
the temperature requirements for each
specimen. “Pathologists rely on quick
turnaround time and excellent sectioning quality from their cryostat,” says
Richard Vernon, Commercial Product
Manager at Thermo Fisher Scientific.
“Our CryoStar NX50 gives them the
functionality and control to achieve
diagnosis rapidly.”
The cryostat is designed with an
LCD touchscreen interface operation
that is streamlined for the user. By
utilising icon driven software, parameters can be changed simply and quickly
to meet the demands of different specimen types.
The NX 50 also offers optional
motorised height adjustment, allowing
the operator to customise the position
of the cryochamber for either seated or
standing operation.
An optional Cold D disinfection
Labotec
Tel: 011 315 5434
Fax: 011 315-5882
Email: [email protected]
system allows
for rapid
decontami
nation of the
cryochamber,
while
protecting
the operator
from exposure
to biological
pathogens with
minimal downtime.
Another feature
is the variablepressure vacutome
that delivers
wrinkle-free
sections by gently
stretching the
specimen during
cutting. ⚛
Antibodies
M
erck Millipore now offers an
extensive and focused portfolio of a number of antibodies and
immunoassays.
With the expertise of Upstate® and
Chemicon®, Merck Millipore provides
validated antibodies with breadth and
depth in the major research areas of:
• Neuroscience
• Epigenetics
• Cell signaling
• Cancer
• Cell structure.
All of
which are
backed
by
excellent service
and support.
Monitor epigenetic changes, such
as histone modification, DNA
methylation or chromatin and
nucleosome remodelling.
Explore the development,
differentiation and degeneration stages with antibodies and
assays for multiple cell, tissue
and organ types.
Decipher the complexity of extracellular, cytoplasmic or nuclear signals
with antibodies, immunoassays and
single cell analysis.
Investigate the relationships between
cancer, apoptosis, autophagy, angio
genesis, metastasis and cell invasion.
Link the structural features to
mechanistic functions of a cell leveraging unique cell adhesion, cytoskeleton
and ECM assays.
Merck Millipore’s highly validated
antibodies are guaranteed for quality
performance. In addition to the validation, all of their antibodies are backed
w ith a best-in-industr y technica l
service team dedicated to their anti
bodies customers.
With the combined expertise of
Chemicon and Upstate, they offer
the most
comprehensive
portfolio of
antibodies
and assays
across the life
sciences industry.
To search their database of
antibodies and select a specific
antibody to suit the needs of a
specific laboratory, please visit
www.millipore.com/antibodies
and find the ‘Antibody
Selection Tool’. ⚛
Merck Millipore
Field Marketing Manager: Adele Heath
Tel: 011-372-5129
Email: [email protected]
Mabtech Antibodies
for Clinical Research
M
abtech develops and manufactures high quality monoclonal
antibodies and kits for ELISA, ELISpot
and FluoroSpot. This company specialises in the development of antibodies
for immunoassays, especially sandwich
immunoassays.
In addition,
the company
supplies
number of
matched
antibody
pairs that
enable highly
sensitive and
specific analysis. The antibodies are also
available as separate
reagents for use in numerous
applications. The product range
includes monoclonal antibodies
for human, non-human primate,
mouse and veterinary research.
Mabtech’s antibodies are suitable for
many applications. The major application areas are ELISA, ELISpot, cell
stimulation, neutralisation, western
blot, cell staining and flow cytometry.
Antibodies are available in purified
form or conjugated to biotin, enzyme
or f luorophore. In sandwich assays,
such as ELISA and ELISpot, purified
antibodies are suitable for capture.
The corresponding biotinylated antibodies are suitable for detection. Antibodies are supplied in PBS with 0.02%
sodium azide for immunoassays. The
antibodies to be used in cell stimulation or neutralisation are supplied free
of preservatives.
Enzyme-conjugated
antibodies, which
enable quicker
assays, are available
for some analytes.
A limited
number of monoclonal antibodies
conjugated to FITC
or Rhodamine for
cell staining and
flow cytometry are also
available.
The majority of the
antibodies are
supplied in standard
quantities of 250µg or 1mg. Larger
quantities are available on request. ⚛
Microsep
Contact: Frances Renwick
Tel: 011-553‑2300
Email: [email protected]