30?
LMS? Issue 6 | 2013
Proteomics
Accelerate Research with the SYNAPT G2-Si
W
aters Corporation has introduced the Waters® SYNAPT ®
G2-Si mass spectrometer along with
the UNIFI® CCS Research Edition
and the TransOmics Version 2.0 informatics products, demonstrating their
benefits for a variety of small molecule
applications and cutting-edge Omicsfocused research.
Waters’ SYNAPT G2-Si system
integrates a third dimension of resolution and separation power into a new
suite of untargeted and targeted LC/
MS/MS workf lows. This powerful
tool gives researchers a means to gain
a deeper understanding of molecular
biology and the disease mechanisms,
to develop the next generation of
healthcare treatments or to screen food
products, or environmental samples for
contaminants.
It combines the power of travelling
wave (T-Wave) ion mobility separations with new data acquisition and
informatics technologies, and collision
cross section (CCS) measurements
to shed light on some of the toughest
analytical applications.
This mass spectrometer is one of the
first MS systems to elevate CCS alongside retention time and mass to charge
ratio as a robust, reliable identification
parameter in library-based screening.
Integrating separation by CCS into
experiments through new high-definition data-directed-analysis and high
definition multiple reaction monitoring
modes benefits analysis.
The SYNAPT G2-Si system can also
separate individual isomers, conformers
and isobaric compounds; help determine sites of biotransformation; study
structure at physiological concentrations; comprehensively profile complex
mixtures and minimise false results in
screening experiments. ?
Microsep
Contact: Louis van Huyssteen
Tel: 011-553?2300
Email: louis.vanhuyssteen@microsep.c o.za
Added Safety with Plastic-Coated Lab Glassware
K
imCote protective glassware
from Kimble Chase is the ideal
choice should you need extremely
durable glassware that can reduce the
hazards of shattered glass and any
toxic leakage.
This range has plastic coating on
the glassware to prevent and contain
any spills in broken glassware with the
advantage of an ultra-clear coating for
easy viewing.
It also has a non-slip surface for
easier handling, whether wet or dry.
Bottles, cylinders, flasks, funnels,
tissue grinders, heavy-duty beakers or
flasks, tube and atmospheric environmental bottles are all available in the
range with the plastic coating.
These items can be used anywhere
where it is needed to increase safety. It
is also resistant to many common lab
chemicals and thus can be used for
chemical storage.
It can also be used for
the transportation of
samples or the
handling of hazardous chemicals and
pressurised glassware. The KimCote
range of glassware features an ultraclear view of the contents of the container and the glassware is steam
autoclavable for easy cleaning and
sterilising.
Features of KimCote
glassware:
• Helps prevent and contain spills in
the event of glassware breakage
• Ultra-clear for improved sample
viewing
• Non-slip surface -wet or dry
• Autoclavable and chemical resistant
• Durable and odour-free. ?
Labotec
Tel: 011 315 5434
Fax: 011 315-5882
Email: sales@labotec.co.za
Fast and Simultaneous 96-Well Manual Pipetting
T
he Liquidator 96 from Rainin (a
Mettler Toledo company), is a
manual bench-top pipettor that provides a convenient, efficient and easyto-use manual pipetting solution to
improve the workflow of many experiments that occur in drug discovery
research. This system allows users to fill
96 or 384-well plates very rapidly and
requires no electricity or set up time.
The Liquidator 96 is easy to use and
has a sturdy, portable design that allows
users to easily move it from bench-top
to laminar f low hood. The system
increases speed and accuracy compared
to hand-held single- or multi-channel
pipettes, and also provides an efficient,
cost-effective alternative to complicated
robotic systems.
The user easily controls the speed
of pipetting with the Liquidator 96.
For rapid filling of PCR master mix
into a PCR plate, for example, the user
can choose the quickest aspiration and
dispensing time. For more viscous
samples or precious samples that need
slower flow rates to prevent shearing,
the researcher can manually slow down
the aspirate and dispense rates.
Rainin’s BioClean tips, which are a
part of every Liquidator 96 run, further
ensure that the researchers avoid any
contamination that can compromise
data integrity.
Minimal training and simple and
routine maintenance ensure that the
Liquidator 96, a unique and flexible
tool that speeds liquid handling, provides top performance and increased
workflow efficiency. ?
Microsep
Contact: Frances Renwick
Tel: 011-553?2300
Email: frances.renwick@microsep.co.za