LIMOUSIN TODAY August 2017 | Page 35

Animal Health Can Storage of Vaccine Affect its Efficacy? By Gant Mourer, Oklahoma State University Respiratory disease in cattle also known as BRD, shipping fever, or pneumonia may cost the U.S. cattle industry over $2 billion annually (Powell 2013). Management techniques can offset much of this cost and having a good vaccination program can maintain the health of a calf all the way through the production system. A vaccine can cost over $3.00 a head, and if not stored properly that vaccine can be rendered in effective. Producers cannot afford to overlook the importance of how they store vaccine and handle it prior to injection. Biological products should be stored under refrigeration at 35 to 45 degrees Fahrenheit unless the nature of the product makes storing at a different temperature advisable (APHIS 2007). If vaccines are not stored within this temperature range, efficacy to the calf can and will be reduced. Killed vaccines are especially susceptible to freezing temperatures. Freezing a killed vaccine will alter the adjuvant or delivery system of a killed vaccine. This, in turn, negatively affects the immune response to the antigen in the vaccine. Modified live viruses (MLV) are more stable but can be in-activated if they are repeatedly cycled above or below the required temperature range (Gunn et al, 2013). Also, once activated by mixing, MLV’s effective life will be reduced to one to two hours and need to be maintained at the 35 to 45 degrees Fahrenheit. This can be accomplished by only mixing the doses that you will use at that time and use a cooler to maintain temperature while working cattle. Researchers from the University of Arkansas and Idaho analyzed the consistency of temperatures for different types, ages and locations of refrigerators over Photo by Todd Johnson, Oklahoma State University Cooperative a 48-hour period. They found Extension that only 26.7 percent and 34.0 percent of refrigerators were How a producer handles vaccine within the acceptable temperature limit outside of the refrigerator is important 95 percent of the time, respectfully. as well. Coolers can easily be modified Refrigerator location can also effect for syringes and are important to temperature. Refrigerators located maintaining vaccine efficiency chute in barns (35.6 ⁰F) were colder than in side. Using a one-and-a-half-inch mud rooms (41.72 ⁰F) and kitchens PVC pipe or sink tail piece purchased (40.82 ⁰F). (Troxel and Barham 2009). at any hardware store and a one- Temperature within a 24-hour period and-a-half-inch hole sa