Lab Matters Winter 2018 - Page 25

environmental health in community members who were not tested. These PFAS Exposure Assessment Technical Tools can be requested by sending an email to PFAS@cdc.gov. directly or through assisting state and federal partners. Additionally, NCEH/ ATSDR initiated a federal inter-agency PFAS coordination group to identify expertise, share current research and identify resources needed to understand the health impact of PFAS exposure. Through epidemiologic investigations with partners, NCEH/Division of Laboratory Science (DLS) provides technical assistance to understand the extent of PFAS exposure and potential health effect s. For example, NCEH/DLS partners with local and state public health laboratories participating in the Laboratory Response Network Chemical Section (LRN-C) to support quality assurance, materials and training for chemical threat emergency programs in local jurisdictions. LRN-C instruments and staff were utilized in a PFAS exposure incident in Hoosick Falls, NY. Supported by NCEH/DLS, LRN-C staff at the New York State Department of Health were able to develop a high-throughput method to measure serum levels of perfluorooctanoic acid and quickly assess the PFAS exposure of over 3,000 residents. ATSDR and state health partners are investigating exposure to and possible health effects associated with PFAS in more than 30 communities across the United States (see map). Currently most sites are related to drinking water contamination connected with PFAS production facilities or firefighting training areas that regularly used aqueous film-forming foam. ATSDR has connected with community groups interested in PFAS through numerous public meetings across the country. In response, NCEH/ATSDR developed educational materials for communities with questions about PFAS exposures and prepared guidance for clinicians for responding to patient exposure concerns. The agency is now considering how best to design a health study on PFAS. The NCEH laboratory is involved in many collaborative studies with partners, and provides technical assistance to understand the extent of PFAS exposure and potential health effects from such exposures for these epidemiologic investigations. PFAS Activities at EPA NCEH/ATSDR has also prepared a statistically-based, practical approach for assessing potential community exposures to PFAS and estimating serum PFAS levels PublicHealthLabs @APHL APHL has been informed of various EPA efforts surrounding PFAS, but one project in particular is of note. Seven APHL member laboratories have volunteered to be part of an EPA PFAS method validation study. EPA has developed a liquid chromatography tandem mass spectrometry method for waters other than finished drinking water. The preliminary internal validation has been completed and EPA is now proceeding APHL.org with an external validation to confirm the accuracy and precision of the method for 24 PFAS analytes in ground, surface and waste waters. Work will likely begin spring 2018 with 5-8 public and private laboratories participating in the study. PFAS Activities at APHL Per- and Poly-Fluoroalkyl Substances (PFAS): Nevertheless, They Persist will be one of the PFAS-related sessions at APHL’s Annual Meeting on Saturday, June 2 from 4-5:30pm PT. PFAS were a topic of great interest at APHL’s recent Environmental Health and Environmental Laboratory Sciences Committees meeting, one the committees will keep tabs on in coming years. And PFAS were a hot topic at the National Meeting of State Biomonitoring Programs in December, hosted at the New Jersey Department of Health, where state public health laboratorians and epidemiologists presented on cutting edge biomonitoring work, such as the study outlined here. n DIGITAL EXTRA: To prepare your laboratory for PFAS testing, email PFAS@cdc.gov Winter 2018 LAB MATTERS 23