Lab Matters Summer 2020 | Page 7

FEATURE The New World Order of COVID-19 By Jill Sakai, PhD, writer On December 31, 2019, the Wuhan Municipal Health Commission in China reported a cluster of cases of pneumonia in Wuhan, Hubei Province to the World Health Organization (WHO), ringing in the new year in ominous fashion. The cause of the pneumonia, the novel coronavirus SARS-CoV-2, swept the globe. Within weeks, the United States had its first confirmed case: a traveler from Wuhan who arrived in Washington. On March 11, WHO declared the COVID-19 outbreak a global pandemic. “We have never before seen a pandemic sparked by a coronavirus,” said WHO Director- General Tedros Adhanom Ghebreyesus, PhD, in his announcement. “And we have never before seen a pandemic that can be controlled, at the same time.” The ensuing global response to do just that has become a defining event of 2020. The scale and duration of the pandemic and its response efforts have revealed strengths and weaknesses in health systems around the world, while also highlighting the creativity and generosity of the human spirit. In the US, public health laboratories pivoted from regular testing and surveillance duties into emergency response mode, operating around the clock, mobilizing staff and coordinating shifts to ensure personal safety, and scrambling to keep their shelves stocked with critical testing supplies. With a hyperfocus on testing throughout the pandemic response, US public health laboratories were thrust into the spotlight for officials, media and the public alike. As they responded with a blend of resilience and ingenuity in the face of testing snafus, crushing workloads and massive supply shortages, it has become clear that SARS-CoV-2 has changed the future course of public health. Early Days On Sunday, January 19, Washington State Public Health Laboratory director Romesh Gautom, PhD, received a call from his microbiology director. The laboratory had received a request to pick up a specimen from a nearby community clinic for coronavirus testing. Laboratory staff and an epidemiologist collected, packaged and shipped the sample to the US Centers for Disease Control and Prevention (CDC). Then they waited. The next evening, the Washington team got the news they had both dreaded and expected: the sample was positive for SARS-CoV-2. The US had its first confirmed case of the novel coronavirus. That day, the Washington State Department of Health activated an Incident Management Team at the building that houses both the state public health laboratory and the communicable diseases epidemiology office. “Forty, fifty, sixty people appeared over the course of weeks,” Gautom recalled. “Our lunchroom was converted into an operation center. Conference rooms were converted into offices to accommodate everyone.” On the national level, APHL was also mobilizing staff and resources to support members. It established its own Incident Command System on January 22 to coordinate with CDC and other federal agencies. At the end of the month, APHL established a COVID-19 Laboratory Task Force with laboratory directors from jurisdictions across the country and initiated weekly calls between public health laboratories and CDC for situational updates and briefings on testing strategies and rollout plans. With that information, laboratories were able to start preparing even before a test was available, acquiring supplies and equipment and training staff. But as the number of specimens mounted, so did the urgency. “Every day, there was a lot of pressure to establish testing here at the lab,” Gautom said. With many travelers from Asia arriving in southern California, the Orange County Public Health Laboratory had been prepping and shipping numerous specimens to CDC. Eager to move testing in-house, the laboratory staff were glad PublicHealthLabs @APHL APHL.org Summer 2020 LAB MATTERS 5