Lab Matters Fall 2023 | Page 54

APHL 2023 POSTER ABSTRACTS

Our objective was to understand the perspective of the frontline and identify common root causes for prominent organizational challenges they faced in daily operations . We gathered insights on how frontline workers overcame those challenges , their priorities , lessons learned , and opportunities for improvement that directly impacted resilient supply chain operations across the private and public health care sectors . We employed a multi-pronged approach by interviewing both supply chain leaders and frontline workers across private and public hospitals to understand their respective views . We also conducted supplemental research consisting of follow-up interviews with the supply chain leaders whom we previously engaged to gain additional insights on the persistent organizational challenges that impact supply chain resilience and what has changed over the past year across people , processes and technologies . This supplemental research served to provide a multiindustry viewpoint via case studies that amplified the significance of key industry-agnostic organizational factors that impact overall supply chain resilience and performance .

Presenter : Sarah Slomski , sslomski @ deloitte . com

Improving Visibility of Quality Indicators Through Automated Dashboarding : An Effective Way to Enhance Laboratory Quality Management System

N . Ruehlen 1 , M . Gomaa 1 , C . Baldwin 2 , V . Aoki 1 ; 1 Washington State Public Health Laboratories , 2 Health Technology Solutions , Washington State Department of Health

Background : Maintaining compliant and robust Quality Management Systems traditionally involve many laborious and manual processes . Manual data collection and analysis activities require dedicated staffing resources , lead to system inefficiencies , and may result in compliance gaps . One example is provided by personnel competency assessment , which is one of the top deficiency findings cited during accreditation inspection associated with Clinical Laboratory Improvement Amendments ( CLIA ) and topped the list in 2021 at 18.96 % ( CMS , 2021 ). Tracking and documenting competency assessments is a challenging task for busy laboratories with hundreds of laboratory staff and extensive test menus . This poster presents development of automated interactive dashboards as a tool to empower Directors and Supervisors to access and view competency assessment status of their staff and take meaningful actions to meet key regulatory requirements . Methods : In 2022 a secure file transfer of weekly backup data for laboratory staff competency assessment records was established with our enterprise quality management program provider ( MediaLab ). Using a SQL query , backup files were compiled into a single database which has been utilized to develop dashboards . Dashboards were developed for each laboratory section with specific focus on Directors and Supervisors as the intended audience . Priority of data displayed was given to competency status ( due soon , in progress , complete , overdue ) of each staff member . Further metrics (% completed and % finished on time ) were included to highlight trends and potential areas for quality improvement . The data model and dashboards were developed using Microsoft PowerBI ( PBI ). Dynamic charting and slicer features in PBI were used to allow users to intuitively interact with the dashboard and quickly navigate to key critical data . Results : Automated dashboards allowed Directors and Supervisors to quickly view the high-level status of competencies and drill into details on a particular competency assessment or see the status of an individual staff member ’ s competencies . While not a metric specifically targeted for dashboarding , an additional outcome of the dashboard allowed Supervisors to identify competencies mismatched to their staff . Conclusions : Development of automated dashboards eases the burden of laborious manual data collection , analysis , and reduces data errors associated with reporting competency assessment information allowing Directors and Supervisors to focus on staff compliance activities . Specifically , metrics such as % finished on time , enables quick identification of problem areas affording rapid actions to improve compliance .

Presenter : Nevada Ruehlen , nevada . ruehlen @ doh . wa . gov

DIAGNOSTICS AND NEW DISEASE TECHNOLOGIES

A Landscape of Infectious Disease In Vitro Diagnostic Devices : From 2000 to Present

E . Bradford , K . Yeh , G . Olinger , R . Soong ; MRIGlobal

In vitro diagnostic ( IVD ) devices encompass a broad range of tests that include infectious diseases and have been used to detect and diagnose pathogens for decades . Recent outbreaks such as mpox and the Sudan ebola virus have led to greater need for IVDs that bring the point of care out of the clinical setting and directly to the user , as exemplified during the COVID-19 pandemic . These point of care ( POC ) devices are ideally portable , functional in low resource environments , easily interpreted , and have limited logistical or storage requirements from manufacturer-to-user . However , this high bar for functionality is supported by novel bioengineering and assay chemistry developments . The rapidly expanding market for infectious disease POC IVDs highlights the need for a practical approach to development that considers a wide scope of factors to include POC characteristics , detection technology , and market assessments including public health to support forward leaning product development . Together , these many factors underscore the need for a clearly defined path from conceptualization to market launch . In this review , we illustrate how Infectious Disease IVD development has evolved while highlighting POC device-specific considerations .

Presenter : Elaine Bradford , ebradford @ mriglobal . org

A Panther Fusion Clade II Mpox Lab Developed PCR Assay - Optimization Using the Open Access System

R . Villa , J . Benfer ; State Hygienic Laboratory at the University of Iowa

Background : Mpox is a double-stranded DNA virus belonging to the Orthopoxvirus genus . In early May 2022 , mpox was reported outside of Central / Western Africa for the first time since 2003 , signifying the beginning of a global outbreak where the U . S . has been leading in cases and deaths . To respond to the outbreak , the CDC recommended the Non-variola Orthopoxvirus Generic Real- Time PCR Test for public health labs to test clinical samples and aid in the detection of mpox . Though this test has reliably served as an important diagnostic tool for many public health labs during the mpox outbreak , there are some aspects- timeliness , labor costs , convenience , and workflow efficiency- that require improvement in