Journal of Rehabilitation Medicine 51-5 | Page 65

Anatomical landmarks for tibial nerve block ned according to surface anatomical landmarks (6–8). The medication is usually injected when the needle tip is in close contact with the targeted motor nerve cor- responding to a (clinically evident) muscular contrac- tion of selected muscles seen at ≤ 1.0 mA intensity and 100 µs duration of stimulation (7). Electromyography (EMG) may also be used to help target the appropriate motor nerve branch by monitoring the H-reflex (8). Diagnostic nerve block (DNB) allows spastic muscle overactivity to be differentiated from contracture, and the respective role of different muscles in spastic over- activity patterns to be determined (6, 7). DNB consists of injecting a small dose of local anaesthetic near to the nerve (motor branches) innervating spastic muscles in order to temporarily suppress their overactivity (6). DNB may lead to a decrease in spastic muscle overac- tivity and clonus disappearance in the selected muscles within a few minutes. The duration of DNB relies mainly on the type of local anaesthetic injected (for example lidocaine is shorter lasting than bupivacaine or ropiva- caine) (9). On the other hand, therapeutic nerve block (TNB) for managing spastic muscle overactivity consists of perineural injection of phenol (in concentrations bet- ween 5% and 7%) or alcohol (in concentrations between 45% and 100%) to obtain neurolysis (7). Spastic muscle overactivity may lead to the deve- lopment of changes in the muscle over time (i.e. cont- racture, atrophy, loss of sarcomeres, accumulation of intramuscular connective tissue, increased fat content, degenerative changes at the myotendinous junction) (10). These local anatomical modifications lead to a mismatch between surface landmarks and the actual position of the spastic muscles (11–14). Therefore, the use of ultrasonography (US) has gained importance in improving botulinum toxin injections for managing some of the most frequent spastic muscle overactivity patterns, such as equinovarus foot (13–15). On this basis, it is plausible that the soft-tissue contracture process due to spastic paresis may also alter the anatomical position of some other key structures for managing spastic mus- cle overactivity, such as motor nerve branches. Thus, the main aim of this study was to identify, by means of US, the anatomical landmarks of tibial motor nerve branches to the gastrocnemii, soleus and tibialis posterior muscles for selective motor nerve blocks in the management of spastic equinovarus foot due to chronic stroke. METHODS This was a single-centre observational study. Inclusion criteria were as follows: age > 18 years; spastic equinovarus foot conse- quent to first-ever unilateral ischaemic or haemorrhagic stroke (documented by a computerized tomography scan or magnetic resonance imaging; subarachnoid haemorrhage excluded); calf muscles spastic muscle overactivity grade of at least 1 on the 381 Modified Ashworth Scale (MAS) (16); at least 6 months since stroke onset; no botulinum toxin injection into the affected leg calf muscles in the 5 months before recruitment. Exclusion criteria were as follows: participation in other trials; fixed cont- ractures (tone grade of 4 on the MAS) or bony deformities at the affected lower limb; previous treatment of spastic equinovarus foot with neurolytic or surgical procedures; other neurological or orthopaedic conditions involving the affected lower limb. All participants were outpatients scheduled to receive selective DNB of tibial motor nerve branches to the gastrocnemii, soleus and tibialis posterior muscles. Written informed consent for par- ticipation in the study was obtained from all patients. The study was carried out accordance with the Declaration of Helsinki and was approved by the local ethics committee. Ultrasonographic evaluation Patients remained in the prone position with their legs outstret- ched during the procedure. All patients underwent real-time B- mode US, performed using a MyLab 70 XVision system (Esaote SpA, Genoa, Italy) interfaced with a linear probe (scanning frequency 15–18 MHz). The examination technique consisted of locating the tibial nerve at the terminal division of the sciatic nerve (in the lower third of the thigh) and distally tracking its motor nerve branches to the gastrocnemii, soleus and tibialis posterior muscles. This, so-called “elevator technique”, enables assessment of nerve shape, echogenicity, thickness and its rela- tion with surrounding tissues (e.g. skin, muscles or vessels) (17). The correct identification of tibial motor nerve branches to the gastrocnemii, soleus and tibialis posterior muscles was checked by means of needle (70-mm, echogenic-coated, 22-gauge needle with length graduation) electrical stimulation (1 Hz frequency and 100 μs duration). The tibial nerve motor branches were located in the space (vertical, horizontal and deep) according to the position of the fibular head (upper end) and a virtual line extending from the middle of the popliteal fossa to the Achilles tendon insertion (8). In addition, the spastic calf muscle echo in- tensity was graded semiquantitatively according to the Heckmatt scale (grade 1: normative; grade 2: increase in muscle echo in- tensity while bone echo is still distinct; grade 3: marked increase in muscle echo intensity and reduced bone echo; grade 4: very high muscle echo intensity and complete loss of bone echo) (18). Clinical evaluation Patients remained in the supine position with their knees exten- ded during the evaluation. The spastic ankle passive range of motion (PROM) was measured using a handheld goniometer. The sensitivity of the measurement was set at 5°. The dorsiflex- ion angle was defined as positive and the plantar flexion angle as negative, taking 0° as the neutral position of the joint (18). The MAS is a 6-point scale grading the resistance of a relaxed limb to rapid passive stretch (0 = no increase in muscle tone; 1 = slight increase in muscle tone at the end of the range of mo- tion; 1+ = slight increase in muscle tone through less than half of the range of motion; 2 = more marked increase in muscle tone through most of the range of motion; 3 = considerable increase in muscle tone; 4 = joint is rigid) (16). For statistical purposes, a score of 1 was considered as 1, and a score of 1+ was considered as 2, and so on, up to a score of 4, which was considered as 5 (19). The MAS was used to evaluate spastic calf muscles tone. Also, the Tardieu scale (TS) was used to evaluate spastic calf muscles tone according to the TS grade, which measured the gain of the muscle reaction to fast stretch in dorsiflexion (0: no resistance throughout passive movement; 1: slight resistance throughout passive movement; 2: clear catch at a precise angle, J Rehabil Med 51, 2019