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134 T. Benz et al. did not permit a causal statement on the effectiveness of the treatment, quantification and comparison of changes in health were possible. The differences in changes in health between the 2 groups were adjusted by cofactors that were unequally distributed at baseline and which possibly confounded the outcome changes. In conclusion, ISP reported lower improvements in state of health after an IPMP than GSP. In the sub- sequent follow-ups, these differences were further accentuated. The reasons for these differences remain unclear, but may have consequences for the future management of ISP in IPMPs. Patients with a migra- tion background may have special needs in therapeutic management and addressing them might enhance the positive outcome in the short- and mid-term. ACKNOWLEDGEMENTS The authors thank all patients for participating in the study and the members of the Pain Center of the rehabilitation clinic “RehaClinic” in Bad Zurzach, Switzerland. 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