Journal of Rehabilitation Medicine 51-1CompleteIssue | Page 18

Effect of AFOs on tibialis anterior EMG Table II. Area under the curve (AUC) of the tibialis anterior muscle and walking speed for the early and delayed group (T1–T4); the mixed model repeated measures analysis within and between groups; and the independent samples t-test between the early and delayed group at T4 Mixed model repeated measures analysis a Early group Delayed group T1 (n  = 14) T2 (n  = 15) T3 (n  = 14) T4 (n  = 15) T1 (n  = 7) T2 (n  = 11) T3 (n  = 11) T4 (n  = 11) AUC of the tibialis anterior, µV, median (IQR) Without AFO SW 21 (11;63) 24 (7;62) 22 (8;63) DS1 12 (5;58) 20 (4;61) 17 (7;67) SS 5 (3;21) 8 (3;12) 8 (4;19) DS2 13 (3;24) 14 (3;43) 20 (4;64) With AFO SW 14 (4;64) 24 (2;53) 15 (4;64) DS1 7 (4;43) 21 (5;51) 14 (4;47) SS 4 (3;10) 9 (3;13) 7 (4;18) DS2 6 (3;25) 14 (3;36) 16 (4;47) 33 23 12 22 (9;81) (12;64) (6;20) (6;52) 18 (6;91) 30 (9;82) 8 (6;21) 24 (5;56) Walking speed, m/s, mean (SD) Without AFO 0.37 (0.19) 0.53 (0.29) 0.56 (0.29) 0.60 (0.31) With AFO 0.38 (0.17) 0.56 (0.28) 0.58 (0.30) 0.64 (0.31) 43 (26;67) 40 (17;90) 23 (7;59) 31 (8;49) 9 (5;34) 8 (6;32) 29 (22;50) 31 (10;46) 45 45 22 39 (25;98) (22;68) (9;47) (20;63) 40 21 11 36 (16;121) (8;105) (5;42) (14;48) – – – – 43 (16;85) 32 (9;48) 5 (6;30) 30 (15;66) 40 21 15 39 (14;112) (9;81) (6;41) (14;63) 37 (16;89) 19 (8;49) 7 (5;36) 23 (9;50) Within groups Between Early, Delayed, groups p-value p-value p-value Independent samples t-test b T4, p-value 0.420 0.922 0.531 0.404 0.310 0.975 0.760 0.225 0.282 0.013 0.007 0.248 0.987 0.119 0.117 0.912 0.207 0.921 0.445 0.192 0.40 (0.25) 0.39 (0.21) 0.51 (0.24) 0.58 (0.26) – 0.40 (0.20) 0.58 (0.24) 0.63 (0.26) a For tibialis anterior, median (IQR) values are presented. Statistical test based on logarithmic transformed data and walking speed included as confounder; b Statistical test based on logarithmic transformed data. AFO: ankle-foot orthosis. Effects of early vs delayed provision of ankle-foot orthoses After 26 weeks (T4), no differences in TA muscle activity between both groups were found in SW (in- dependent samples t-test p = 0.310 and p = 0.207 for without and with AFO, respectively) or any of the other sub-phases of gait (p ≥ 0.192 in all cases). Furthermore, mixed-model repeated measures analysis between- groups shows that changes in TA activity during the 26-week follow-up period were not different between the early and delayed group in SW (p = 0.987) or any of the other sub-phases of gait (see Table II). Effects of use of ankle-foot orthoses within a single measurement session TA activity without and with AFO were compared at T4 for the total group (n = 26) to study the effects of AFO use within a measurement. AFO use significantly 15 Fig. 2. Boxplots of tibialis anterior area under the curve (AUC) without ankle-foot orthoses (AFO). AUC is presented per sub-phase, for the early (left) and delayed (right) group separately. Circles and asterisks represent outliers and extreme outliers, respectively J Rehabil Med 51, 2019