Journal of Rehabilitation Medicine 51-1CompleteIssue | Page 12

Predictors of dropout: a systematic review 9 literature with regard to the topic of dropout is still in the stage of model development, this is defined as type 1A studies, according to the TRIPOD statement (37). Since no internal or external validation was considered in the studies included in this systematic review, the results should be interpreted with care. session evaluation of progress and define no fixed length of the programme (10–13, 39). This systematic review will challenge clinicians and researchers to pay more attention to dropout and collaborate in developing strategies to overcome dropout in order to generate bet- ter outcomes in chronic pain management programmes. Strengths Conclusion Since Turk & Rudy addressed the topic of dropout in the early1990s, little high-quality research has become available, as shown by this systematic review. The ma- jority of research on dropout in interdisciplinary pain management programmes for chronic musculoskeletal pain has relied on the investigation of differences bet- ween dropouts and programme completers at baseline or univariate analyses of one variable associated with dropout. To our knowledge this is the first systematic review on dropout in chronic musculoskeletal pain patients in the rehabilitation setting. A strength of this review is that it provides an overview of predictors of dropout in chronic musculoskeletal pain: 63 potential predictors of dropout in univariate analyses and 48 out of 63 potential predictors were investigated in multiple logistic regression analyses. This systematic review presents an overview of pre- dictors of dropout. The literature with regard to the prediction of dropout has focused mainly on patient characteristics and is still in the stage of model deve- lopment. Future research might also focus on therapist/ therapy-related predictors and the interaction between these predictors. This review suggests future research on this topic, in order to generate better outcomes in interdisciplinary pain management programmes. Implications and future directions Dropout is still a neglected topic in daily practice and in research in interdisciplinary pain management. Learning from the abundant amount of research that has been done in the mental health literature recom- mendations for future directions can be specified. One direction could be to perform exit interviews with dropouts to investigate reasons for dropout. Based on these reasons for dropout, strategies may be developed to prevent dropout in future (39). Another direction is to address factors that are predictive for dropout in clinical assessment and to make a distinction whether predictors are modifiable or non-modifiable. For example, younger age is a predictor for dropout in chronic pain management programmes. This predictor is non-modifiable and may be addressed by modifying the treatment schedule. Other strategies that have been developed in the mental health literature that may also be applied in interdisciplinary pain management programmes are: to focus on the assessment of patient’s expectations and preferences and motivation before treatment onset and during the treatment programme, to provide education to address patient’s expectations, preferences and mo- tivation, to monitor the work-alliance between patient and therapist and create the possibility for patients to give feedback to the therapist. Since dropout patients are all different, ideally, prediction of dropout would use prospective cohort designs including session by ACKNOWLEDGEMENTS The authors thank Josca Snoei and Liedeke van Schoot at the University of Applied Sciences Utrecht for their help with the initial construction of this systematic review. The authors also thank Rob Scholten of the Dutch Cochrane Centre for his advice on the best evidence synthesis of this review. Funding sources: This study is supported by grants of the Dutch government- NWO- 023.004.121 and SIA Raak 2012-14-12P. Systematic review registration number: CRD42016039689. The authors have no conflicts of interest to declare. REFERENCES 1. Andrews NE, Strong J, Meredith PJ. Activity pacing, avoid- ance, endurance, and associations with patient functioning in chronic pain: a systematic review and meta-analysis. Arch Phys Med Rehabil 2012; 93: 2109–2121. 2. De Rooij A, Roorda LD, Otten RHJ, van der Leeden M, Dekker J, Steultjens MPM. 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