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870 E. A. Bateman and R. Viana with the general population, other factors that increase a physician’s risk of developing burnout vary by study, with few studies yielding reproducible results (1, 2, 9–12). Among the heterogeneous findings, individual, system, institutional, and patient factors have been shown to play a role (4, 6, 10, 12). Medical specialty has been shown to play a role in predisposing specialists and trainees to burnout, but the specialties found to be at highest risk varies by study (1–3, 10–11). Little is known about burnout in PM&R. In their role caring for persons with disabilities and after catastrophic accidents, physiatrists are adept at fostering resilience amongst their patients, which may confer resilience as physicians, although the high de- gree of empathic demand may, conversely, increase the risk of emotional exhaustion. This systematic review aims to consolidate available literature to enhance our understanding of this critical problem in a potentially vulnerable physician population. Data extracted included number of participants, recruitment met- hod, participant characteristics (career stage, sex, age), country of study, year of publication, study methodology, tool or criteria used to assess burnout, incidence and severity of burnout and, if available, prevalence of depression, suicide, measures of well- ness including resiliency and satisfaction, and risk or protective factors. Data were compiled using a standardized collection form. Data analysis Data were analysed using descriptive statistics. Content analysis was performed for qualitative data. Risk of bias was assessed using the Cochrane Risk of Bias Tool (14). RESULTS METHODS To evaluate the prevalence of burnout in PM&R specialists and trainees. This systematic review was registered with the International Prospective Register of Systematic Reviews (PROSPERO, registration #CRD42018104133). Inclusion criteria www.medicaljournals.se/jrm All studies meeting the inclusion criteria were cross- sectional surveys. Their characteristics and findings are Articles Identified MEDLINE (n=284) CINAHL (n=22) EMBASE (n=43) Hand Search (n=10) Total # Articles Identified (n=359) Duplicates (n=128) Systematic literature searches were conducted in MEDLINE, CINAHL and EMBASE for peer- reviewed full text articles and published abstracts in English published before 1 July 2018, using a com- bination of keywords and Medical Subject Headings (MeSH). The search strategy is shown in Appendix I. Hand searches of studies for which the full text was re- viewed were used to identify other relevant citations. During manuscript preparation, the authors became aware of additional potentially relevant publications from September 2018 and January 2019, after the initial systematic review search strategy was com- pleted. Updated systematic searches were performed in February 2019 using the same search strategy to ensure the inclusion of relevant studies. The authors became aware of a retraction and replacement (13) applicable to one of the included studies during the course of manuscript preparation; the reasons for retraction were reviewed and data extracted was revised to reflect the replacement. Citations obtained from the searches were screened for eligibility by 2 independent reviewers (EAB and RV). Disagreements Study features # Articles after Duplicates Removed (n=231) Potentially Relevant Studies (n=33) Search strategy Studies reporting the prevalence of burnout in specialists and/ or residents in PM&R were included. Studies that grouped PM&R specialists or residents with healthcare providers from other medical disciplines were excluded, unless PM&R-specific outcomes were reported separately. The search strategy yielded 359 articles, of which 128 were duplicates. A total of 33 articles underwent full text review, and 5 met the inclusion criteria (Fig. 1). Four articles (1, 2, 11, 12) were peer-reviewed publications, and one (15) was a peer-reviewed abstract. Cohen’s kappa was 0.89 between the 2 reviewers, indicating excellent agreement in identifying the relevant studies. # Articles Undergoing Full Text Review (n=33) Data extraction Study selection Objective between the reviewers were resolved by discussion to reach consensus. Agreement between reviewers was determined using Cohen’s kappa. Total # Studies Included (n=3) Removed by Screening Abstracts Non-Physician Health Professional (n=69) Patient or Non-Physician Caregiver (n=49) Non-PM&R Physician (n=36) Non-Bumout or Wellness Outcome (n=24) Comment or Opinion (n=8) Not English (n=12) Removed by Full Text Review Non-Physician Health Professional (n=12) Patient or Non-Physician Caregiver (n=3) Non-PM&R Physician (n=5) Non-Bumout or Wellness Outcome (n=3) Comment or Opinion (n=85) Fig. 1. PRISMA study selection flow chart. Flow chart of strategy used for study selection.