Journal of Rehabilitation Medicine 51-10 | Page 45

Pain catastrophizing and dropout in chronic pain management 765 Table II. Scores of completers and dropouts on categories of the Extended Common-Sense Model of Self-Regulation Categories E-CSM Illness representations Brief IPQ – Consequences 1 Brief IPQ – Timeline 2 Brief IPQ – Personal Control 3 Brief IPQ – Treatment Control 4 Brief IPQ – Identity 5 Brief IPQ – Concerns 6 Brief IPQ – Comprehension 7 Brief IPQ – Emotion 8 Treatment beliefs TBQ Necessity TBQ Concerns TBQ Practical Barriers Pain Self Efficacy PSEQ-Pain Self-Efficacy total score Anxiety and Depression HADS Anxiety HADS Depression Pain catastrophizing Pain catastrophizing – Helplessness Pain catastrophizing – Magnification Pain catastrophizing – Rumination Pain catastrophizing – Total Score T0 completers Mean (SD) 7.86 7.45 4.03 7.38 7.75 6.91 6.12 6.52 T1 completers Mean (SD) (1.56) (2.06) (2.28) (1.61) (1.68) (2.11) (2.39) (2.39) 5.93 6.88 5.36 6.77 5.97 4.78 6.91 5.28 (2.70) (2.79) (2.61) (2.52) (2.69) (2.94) (2.56) (2.85) T0 completers T1 completers p-value 0.000* 0.001* 0.000* 0.009* 0.000* 0.000* 0.004* 0.000* T0 dropouts Mean (SD) 8.17 7.34 3.66 6.69 7.43 7.00 5.89 6.91 T0 completers/dropouts p-value (1.52) (2.22) (2.72) (2.29) (2.05) (2.40) (3.14) (2.57) 0.287 0.794 0.453 0.096 0.399 0.836 0.683 0.415 22.37 (3.00) 4.90 (1.86) 3.59 (1.90) – – – – – – 22.21 (3.00) 5.03 (1.77) 4.26 (2.17) 0.777 0.707 0.098 33.71 (11.88) 40.42 (13.86) 0.000* 29.51 (11.97) 0.067 8.87 (4.31) 8.22 (4.71) 7.76 (4.57) 6.15 (4.79) 0.000* 0.007* 9.15 (4.69) 8.89 (4.50) 0.067 0.434 9.82 (5.46) 2.54 (2.49) 7.72 (4.01) 20.08 (10.59) 6.76 (5.75) 2.01 (2.44) 5.63 (4.08) 14.40 (11.47) 0.000* 0.007* 0.000* 0.000* 14.03 (5.44) 3.63 (3.30) 9.77 (4.06) 27.43 (10.98) 0.001** 0.073 0.009** 0.001** *Completers T0 vs. T1 p  < 0.05, **Completers T0 vs. Dropouts T0 p  < 0.05. No statistical analyses on the T1 Dropouts, since only 6 of 35 post-treatment assessments were available. SD: standard deviation. HADS: Hospital Anxiety and Depression scale; PSEQ: Pain Self Efficacy Questionnaire; IPQ: Illness Perception Questionnaire; E-CSM: Extended Common-Sense Model of Self-Regulation. TBQ: Treatment Beliefs Questionnaire. Significant values are shown in bold. Pain self-efficacy (PSEQ – total score). Another po- tential predictor that scored below a p-value < 0.20 was the total score of the PSEQ (p = 0.063). Lower scores on the PSEQ – total score were associated with dropout (Table SII 1 ). Anxiety and depression (HADS – 2 domains). No as- sociations with dropout were found for the 2 domains of the HADS: Anxiety (p = 0.735) and Depression (p = 0.444) (Table SII 1 ). Pain catastrophizing (PCS total score and 3 domains). In univariate logistic regression analyses significant associations with dropout were found for all 3 domains of the PCS: Helplessness (p < 0.001), Magnification (p = 0.034), Rumination (p = 0.009) and the PCS total score (p = 0.001). Higher scores on the all 3 domains of the PCS and the PCS total score were associated with incidence of dropout (Table SII 1 ). Multiple logistic regression analyses Based on the univariate logistic regression analyses 7 predictors for dropout of the 18 selected potential predictors (out of four categories of the E-CSM Self- Regulation were eligible for inclusion in the multiple logistic regression analyses. Because the number of dropouts in this prospective cohort study was limited, maximal 3 of the 7 potential predictors could be in- cluded in the multiple logistic regression model (29). The Brief IPQ item treatment control was chosen for inclusion above the TBQ domain Practical Barriers, since the psychometric properties of this measurement were better than the TBQ (21). In addition, the PCS total score was preferred to the 3 domains of PCS for multiple logistic regression analyses, as these domains were highly correlated with each other (helplessness, magnification and rumination). The following 3 potential predictors were included in the multiple logistic regression analysis: IPQ-B tre- atment control item, PSEQ- total score and PCS total score. Only the PCS total score (p = 0.001) was retained as a predictor for dropout in these analyses. Brief IPQ item treatment control (p = 0.081) and PSEQ- total score (p = 0.770) were not significantly associated with dropout, when adjusted for PCS total score (Table III). In this IPMP an increase of 1 point on the PCS total score resulted in an 1.1 higher odds of dropping out (95% CI 1.028; 1.1071). Bootstrapping was performed using the Bias- Corrected and Accelerated (BCa) bootstrap method with 10,000 draws from the data to internally validate the prediction model. This led to a somewhat broader Table III. Result of multiple logistic regression analysis of potential predictors for dropout (PCS total score, Brief IPQ item treatment control, PSEQ total score) Pain Catastrophizing Total score B SE p LR OR 95% CI Wald 0.065 0.019 0.001 1.067 1.028; 1.107 ROC curve and area under the curve: 0.688 (95% CI 0.589; 0.786), Hosmer- Lemeshow test: (p  = 0.508). PCS: Pain Catastrophizing Scale; IPQ: Illness Perception Questionnaire; PSEQ: Pain Self Efficacy Questionnaire; OR: odds ratio; CI: confidence interval. J Rehabil Med 51, 2019