JCDA Jan 2014 | Page 10

Sensodyne Repair & Protect ® Powered by NovaMin® Patented calcium and phosphate delivery technology Sensodyne Repair & Protect is the first daily toothpaste to contain NovaMin® plus fluoride, a unique technology proven to help repair exposed dentin.1 • Delivers calcium and phosphate into the saliva1–3 to form a reparative hydroxyapatite-like layer over exposed dentin and within dentin tubules.2–11 Repairing exposed dentin NovaMin® builds a reparative hydroxyapatite-like layer over exposed dentin and within the tubules2–11 that: • Starts building from first use1 • Is up to 50% harder than natural dentin12 • Provides continual protection from dentin hypersensitivity with twice-daily brushing13–15 Building a hydroxyapatite-like layer over exposed dentin and within dentin tubules2,8–11 Protecting patients from the pain of future sensitivity The reparative hydroxyapatite-like layer firmly binds to collagen in dentin.1,16 In vitro studies have shown it is: • Built up over 5 days1 • Resistant to toothbrush abrasion1 • Resistant to chemical challenges, such as consuming acidic food and drinks1,8,12,17 5 µm Fluoridated hydroxyapatite-like layer over exposed dentin Fluoridated hydroxyapatite-like layer within the tubules at the surface In vitro cross-section SEM image of hydroxyapatite-like layer formed by supersaturated NovaMin® solution in artificial saliva after 5 days (no brushing).10 Adapted from Earl J, et al.10 /® or licensee GlaxoSmithKline Consumer Healthcare Inc. Mississauga, Ontario L5N 6L4 ©2014 GlaxoSmithKline TM Think beyond pain relief 1. Earl J, et al. J Clin Dent. 2011;22(Spec Iss):68–73. 2. LaTorre G, et al. J Clin Dent. 2010;21(Spec Iss):72–76. 3. Edgar WM. Br Dent J. 1992;172(8):305–312. 4. Arcos D, et al. A J Biomed Mater Res. 2003;65:344–351. 5. Greenspan DC. J Clin Dent. 2 ĽJ