Ispectrum Magazine Ispectrum Magazine #10 | Page 38

Is the tulasi safe for humans? Toxicity or safety study of tulasi: In a study by Chandrasekaran CV et al, scientists employed the standard battery of in vitro genotoxicity tests, namely bacterial reverse mutation, chromosome aberration and micronucleus (MN) tests, to assess the possible mutagenic activity of tulasi on rats. Tulasi extract did not show structural chromosomal aberrations or increase in MN induction, with and without S9, at the tested dose range in both 4-h and 18-h exposure cell cultures. Thus, it was concluded that tulasi extract is not genotoxic in bacterial reverse mutation, chromosomal aberration and micronucleus tests. In an acute oral toxicity test, rats were treated with 5 g/kg of OciBestâ„¢ and observed for signs of toxicity for 14 days and the results did not show any treatment-related toxic effects to Wistar rats [17]. Thus, we can say that this wonder plant Tulasi (Ocimum Sanctum or Holy Basil) can offer a ray of hope for cancer patients. Still, large numbers of randomized clinical trials are needed to establish tulasi as effective weapon against one of the deadliest enemy of humanity, cancer. We, as scientists, should use this opportunity effectively which Mother Nature has offered to us. 37