Ispectrum Magazine Ispectrum Magazine #09 | Page 57

compared to current alternatives”. for example. Scientists exposed honeybees to the spider venom molecule at a range of concentrations, ranging from minute doses to doses so high that they would never be seen in a field setting. After completing the research the team found that the new biopesticide did not pose a significant risk to honeybee health. In fact, the spider venom molecule was about as harmless to honeybees as a nontoxic control substance, Nakasu said: “The fact it can selectively kill insect pests, but not bees, was actually surprising”, he went on to say: “we consider the molecule to be relatively safe to bees, particularly when the new biopesticide did not pose a significant risk to honeybee health 56 The exact reason why this new biopesticide is harmless to bees and toxic to other pests is not completely clear. But it seems to be related to the spider venom molecule’s effect on ion channels, which are proteins found in the lining of all cells. These proteins control the flow of charged ions in and out of the cell, and are vital for many important physiological processes. It appears that the spider venom molecule targets and inhibits a particular type of ion channel in the cells of the pest insect, causing mortality. This process doesn’t seem to happen in honeybees and this may be because they have a slightly different version of the ion channel found in pest species. This different type of ion channel may not be susceptible to the spider venom molecule, making honeybees resistant to the molecule. The lab group at the University of Newcastle is currently completing research to confirm this theory.