Historical Information
Natural Role Within the Human Body
de-1
Tripeptide-1 )
Molecular structure of Tripeptide-1 ( Copper Tripeptide-1 ) son for referring to this ingredient as Tripeptide-1 ( Copper Tripeptide-1 ) in the iS Clinical material is for convenient internet searching by prospective professionals and consumers and to hopefully limit confusion as to the form of the ingredient used in our products .
Historical Information
When this molecule was first described , it was thought to be a growth factor 1 and was referred to as such . The original research revealed that it caused aged liver cells to become metabolically young again . Hepatocyte Growth Factor ( HGF ) had this same uncommon activity , and the molecules were thought to be identical . However , further research showed that these were , in fact , very different molecules even though they shared this same quality . Tripeptide-1 ( Copper Tripeptide-1 ) is now known to fit best within the family of cytokines , which are messenger molecules . It is sometimes termed a “ matrikine ,” 2 referring to it as a mother cytokine because it possesses a wide variety of properties and functions .
Growth factors are large molecules composed of over a hundred individual amino acids . Tripeptide-1 ( Copper Tripeptide-1 ) is a very small molecule composed of three amino acids – glycine , histidine , and lysine – joined with copper . It may be abbreviated as GHK-Cu , using the official abbreviations for its four chemical constituents .
Natural Role Within the Human Body
Tripeptide-1 ( Copper Tripeptide-1 ) is a bio-identical molecule , i . e ., it exists naturally within the human body and is exactly like the molecule found within the human body . There are two sub-forms of it , one containing copper ( GHK-Cu ) and one without copper ( GHK ). The molecule containing copper functions more advantageously than the one without copper , but both are used by the human body . The molecular structure of this substance has never changed ; it has always been GHK-Cu even though INCI terminology has called it by different names over the past decades . And adding to the confusion , when one searches the medical literature – as seen in the reference list - even more names will be found .
Although our focus is on skin , Tripeptide-1 ( Copper Tripeptide-1 ) is so important that it is found within all tissues , where it exhibits a surprisingly diverse array of maintenance and repair functions . 3 Injured tissue contains large amounts of it and it acts as a signaling agent for repair and regeneration . 4 It signals the synthesis of collagen , elastin , and glycosaminoglycan ( GAG ) ground substances . 5 The considerable anti-aging qualities of Tripeptide-1 ( Copper Tripeptide-1 ) were described early-on via its transformation of aged liver cells into metabolically younger cells 6 and in subsequent work , to be detailed later on .
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