Ingredient Focus : Superoxide Dismutase ( SOD ) | by Dr . Charlene DeHaven
yeast . This allows for the design of a unique topical form that is carried through the skin .
SOD is one of 4 powerful antioxidants existing within the human body . As a bio-identical substance , the skin recognizes it as its own and uses it readily . It is also an enzymatic antioxidant and
SOD is one of 4 powerful antioxidants existing within the human body .
Increasingly protective effect can renew itself to act again as an antioxidant . SOD neutralizes the superoxide radical , one of the most devastating free radicals .
SOD Catalase
Glutathione peroxidase ( GPx )
Glutathione , CoQ 10 Carotenoids , Vitamin E Flavonoids , Vitamin A , C Trace elements , Proteins
Essential enzymes
Complete defense system
Classical antioxidants
Play a buffering role but are rapidly saturated
The ultimate choice of antioxidant ( s ) for a final product depends upon many factors , including quality of the product ( pH , viscosity , solubility , others ), quality of the other ingredients , overall goal for the product ’ s actions , and place in the skincare regimen . Thus , the same antioxidant cannot be used over and over in all products .
In studies using topical SOD , molecules associated with both free radical damage and protection from it were measured . In situations where free radical damage would usually occur , the presence of SOD caused improvements in the messengers associated with damage and oxidative stress . Included in these was prostaglandin E2 ( PGE2 ), a very active pro-inflammatory molecule . Topical SOD completely prevented the formation of PGE2 in the arachidonic acid cascade . PGE2 is involved in most , if not all , types of inflammatory responses , ranging from sunburn to skin cancer development . In these situations , the topical SOD decreased the formation of oxidative stress byproducts and protected cell membranes from damage more effectively than the more commonly used non-enzymatic antioxidants .
Studies done on the topical form of SOD used by iS Clinical show that it is absorbed into the skin and reduces free radical damage . This SOD protects against lipid peroxidation in delicate skin cell membranes , neutralizes the dangerous superoxide radical , protects
The pyramid above explains the high antioxidant protection afforded by SOD compared to other antioxidants .
68 iS Skin Source