brinogen within our blood is converted to fibrin by thrombin in the early stages of clot formation 5 . Due to PRF ’ s higher platelet count , the consistent release of growth factors , less blood needed from the patient , and the fact that PRF does not contain anticoagulants , PRF may ultimately be the top choice for patients and most effective at reducing fine lines , discoloration , and texture when compared with PRP .
The Procedure and Results
PRP and PRF are most effective in a series of treatments to achieve the most corrective and rejuvenating results . When used with micro needling , a series of 4 sessions is spaced 3 to 6 weeks apart . When performed as an injection , the spacing is 3 to 6 months apart , several times a year as needed . The treatments are minimally invasive with no recovery time required and safe for all skin types , including dark or sensitive skin . The possibility of an allergic reaction is negligible because the plasma comes from the patient ’ s own body . Results from PRF or PRP can take a few months to see and can last for up to a year . The PRF treatments provide
PRP and PRF are most effective in a series of treatments to achieve the most corrective and rejuvenating results .
even longer-lasting results as they continue to release growth factors over time . The treatment results vary for each patient due to several factors such as age , underlying skin issues , and at-home regimen . Side effects are rare but may include possible erythema , ecchymosis , and swelling . Typically , these effects are self-limiting and resolve within two weeks . 4
In summary , both PRP and PRF offer an exciting and effective new development in the realm of cosmetic science . PRP and PRF are two safe and effective concentrates , providing a natural option for those looking to improve overall skin integrity , collagen synthesis , and optimal gene expression , with the end goal of reversing the signs of aging .
References :
Khan AI , Anwer F . Platelet transfusion . In : StatPearls [ Internet ]. Treasure Island ( FL ): StatPearls Publishing ; 2022 [ cited 2022 Feb 5 ]. Available from : http :// www . ncbi . nlm . nih . gov / books / NBK560632 /
Raval JS , Griggs JR , FlFlag . Blood product transfusion in adults : indications , adverse reactions , and modifications . AFP . 2020 Jul 1 ; 102 ( 1 ): 30 – 8 .
Hassan H , Quinlan DJ , Ghanem A . Injectable platelet‐rich fibrin for facial rejuvenation : A prospective , single‐center study . J Cosmet Dermatol . 2020 Dec ; 19 ( 12 ): 3213 – 21 .
Lin M-Y , Lin C-S , Hu S , Chung W-H . Progress in the use of platelet-rich plasma in aesthetic and medical dermatology . J Clin Aesthet Dermatol . 2020 Aug ; 13 ( 8 ): 28 – 35 .
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