thermal as well as non-thermal treatment (in combination with high pressure and high intensity
pulsed electric fields) are driving the Nisin market exponentially. Other applications like an agent in
veterinary, healthcare, and pharmaceutical products, and as an agent for isolation of yeast, gram-
negative bacteria, and moulds will open new avenues for the Nisin market on the forecast horizon.
However, disadvantages of Nisin like less effectiveness in high fat foods and adsorption to the
surface of protein globules, flavor alteration in dairy products, resistance development by microbes,
inhibition of beneficial microflora, and proteolytic enzymes in raw roods that may inactivate nisin
are restraining market growth.
Nisin is a bactericidal polypeptide that inhibits closely related species that are spoilage bacteria,
thus acts as a preservative without hampering taste and color. It is a byproduct of lactic acid
fermentation with working mechanisms like cell death, leakage of molecules, bind to receptor, and
pore formation. It is commonly known as Nisin Bacteriocin. It works best in combination with other
antimicrobial (Monolaurin, LPS, or other bacteriocins) and in low fat having pH value less than 6.
Nisin is usually produced by a fermentation process using Lactococus bacteria. To overcome the
disadvantages of nisin, it was microencapsulated in phospholipid vescicles and tested on Cheddar
cheese. This improved its stability, distribution, and efficacy; as cited in International Dairy Journal
in 2003. Nisin is the only natural preservative approved by FDA as well as WHO.
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Nisin market is segmented on the basis of application and the geographical region. The application
based segments include canned vegetables, meat, pasteurized dairy products, bakery products,
beverages, and others. The geographical regions for this market are Asia Pacific, Europe, North
America, and Rest of the World (RoW).
Meat segment currently holds the largest market share, particularly in US & Europe, due to high
consumption of meat and seafood in these regions. On the other hand, canned vegetables segment
is expected to reach the high water mark in terms of CAGR in the forecast period due to various
applications of nisin for preserving as well as active packaging of canned vegetables. North America
leads the current Nisin market, with US on the forefront. This is due to the high demand for