Description :
Bone grafts are implantable materials that promote bone healing through its osteoconductive , osteogenic , and osteoinductive mechanisms . The bone grafts are used in surgical procedures such as spinal fusion surgeries , bone replacement , ensuring new bone formation and repair of bone fractures . Moreover , bone grafting also has applications in treatment of various bone related disorders such as congenital pseudoarthrosis , dental bone grafting problems , and complex fractures . Allografts , synthetic bone grafts , and demineralized bone matrix are the most commonly used bone grafts worldwide .
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The world bone grafts and substitutes market was $ 2,443 million in 2015 and is expected to reach $ 3,397 million by 2022 with a CAGR of 4.1 % during the forecast period . Rise in incidences of musculoskeletal disorders , development of biocompatible synthetic bone grafts , technological advancements in medical field leading to a shift from autograft to allograft drive the bone grafts and substitutes market . According to National Health Interview Survey , in 2012 , around 126 million adults were affected by musculoskeletal disorders in U . S . Moreover , the 2014-2015 estimates from Labor Force Survey ( LFS ) showed 553,000 cases out of a total of 1,243,000 for all work related musculoskeletal disorder . These estimates are expected to boost the demand for bone grafts and its substitutes in the coming years . In addition , increase in cases of lifestyle disorders such as diabetes and obesity add to the risk of developing degenerative joint diseases that further fuel the growth of the market .
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On the other hand , high cost of surgeries and ethical issues related with bone grafting procedures restrict the market growth . Conversely , emerging markets , rise in interests of key players towards R & D activities in bone grafts and its substitutes , and increase in demand for orthopedic procedures particularly in geriatric population is expected to provide lucrative opportunities for growth of the market in near future .
The report segments the market based upon product type , application , and geography . Based on product type , the market is segmented into allografts , bone grafts substitutes , and cell based matrices . The allografts are further categorized to machined allografts and demineralized bone matrix . The bone graft substitutes segment is further classified into bone morphogenic proteins ( BMP ) and synthetic bone grafts . Based on applications , the market is segmented into spinal fusion , trauma , craniomaxilofacial , joint reconstruction , and dental bone grafting . Geographically , the market is segmented into four major regions , namely , North America , Europe , Asia-Pacific , and LAMEA .
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