Population , Problem , or Patient
This refers to the specific group of individuals or subjects under investigation . It can include characteristics such as age , gender , medical condition , or any other relevant demographic information .
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Intervention or Exposure
This defines the specific intervention or exposure being studied . It could be a treatment , therapy , diagnostic tool , preventive measure , or any other intervention of interest . This intervention should be described in detail to ensure clarity .
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Comparison
In some research questions , it is important to compare the intervention to an alternative or control group . The comparison group can be a placebo , standard treatment , or any other relevant comparison point .
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Outcome
This refers to the desired or measured outcome of the study . It could be a clinical outcome , a change in behavior , quality of life improvement , or any other measurable endpoint . It is important to define the outcome to ensure the research question is focused .
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