ILAS PG Conference | Page 43

Anya Osborn School of Life Sciences Assessment of cells associated with age-related hearing loss Age-related hearing loss is thought to be caused by the degeneration of cells called fibrocytes in the inner ear. Our hypothesis is that replacing these fibrocytes may prevent this degeneration and restore this type of hearing loss. But before this, there must be a comparison of between the original fibrocytes and the replacement fibrocytes in terms of whether they appear and function in a similar way. The aim being to characterise the properties the fibrocytes possess which are involved in functioning of the hearing process. Confirmation that the replacement fibrocytes that are grown in the laboratory express similar characteristics to the original fibrocytes in the organism will allow us to develop a novel strategy for growing these cells in a transplantable form. Postgraduate Conference 2016 Page 42