*Dr. Himanta Bansal
**Dr. George Koshy
***Dr. Alka D. Kale
***Dr. Rashi Behl
The Journal
An unusual case of Dentinogenic ghost cell tumor with
Adenomatoid odontogenic tumor features
Dentinogenic ghost cell tumor is an extremely rare odontogenic tumor and accounts for only 2% to
16% of all Calcifying Odontogenic Cysts. Dentinogenic ghost cell tumor was first described by
praetorius et al in 1981 as a neoplastic variant of Calcifying Odontogenic Cyst. We report an unusual
case of Dentinogenic ghost cell tumor that occurred in left posterior mandible of a 25 year old man.
The tumor showed nests or clusters of proliferative odontogenic epithelium with ghost cells and
massive juxtaepithelial tubular dentinoid material, diagnosed as Dentinogenic ghost cell tumor. The
interesting and prominent feature was presence of Glandular/ ductal pattern of epithelium with
eosinophilic coagulum, amyloid and dystrophic calcification, features resembling
Adenomatoidodontogenic tumor. After the surgical removal, the patient was recalled for periodic
follow up and has remained symptom free for the last 8 years.
Introduction
Dentinogenic ghost cell tumor is an extremely
rare odontogenic tumor and accounts for only
2% to 16% of all Calcifying Odontogenic Cysts.
Dentinogenic
ghost cell tumor was first
described by praetorius et al in 1981 as a
neoplastic variant of Calcifying Odontogenic
Cyst. We report an unusual case of
Dentinogenic ghost cell tumor that occurred in
left posterior mandible of a 25 year old man. The
tumor showed nests or clusters of proliferative
odontogenic epithelium with ghost cells and
massive juxtaepithelial tubular dentinoid
material, diagnosed as Dentinogenic ghost cell
tumor. The interesting and prominent feature
was presence of Glandular/ ductal pattern of
epithelium with eosinophilic coagulum, amyloid
and dystrophic calcification, features
resembling Adenomatoidodontogenic tumor.
After the surgical removal, the patient was
recalled for periodic follow up and has remained
symptom free for the last 8 years.
Case Study
A 25 year old man reported to the department,
with complaints of pain and swelling in the lower
left posterior region of mouth since 1 month.
The patient gave history of trauma in the same
region 5 years back and a small swelling which
had been gradually increasing in size. On
extraoral examination a diffuse swelling
measuring approximately 4x3 cms in size was
observed in the left body of the mandible. The
overlying skin was stretched but normal in
colour. There was no local rise in the
temperature.
Fig 1
Intraorally, the swelling was seen in the left
mandibular premolar-molar region resulting in
the obliteration of the vestibule. The mucosa
over the swelling was intact and normal in color.
*Professor & HOD, Department of oral and maxillofacial Pathology, BJS Dental College, Hospital & Research Institute Ludhiana, Punjab, India
**Professor & HOD, Department of Oral and Maxillofacial Pathology, Christian Dental College, Ludhiana, Punjab, India.
***Principal and Professor, Department of Oral and Maxillofacial Pathology, K.L.E.S Dental College, Belgaum, Karnataka, India.
****Professor, Department of Oral Surgery, BJS Dental College, Hospital & Research Institute Ludhiana, Punjab, India.
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Vol. 13
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May-August
Sept-Dec 2017
Jan-April
2016
2016