with a total cost of €85.00.
The differential total costs were
+€10.46, +€27.07 and +€23.05 for
Apr+Ond, Apr+Pal and Fos+Gra,
respectively. 15
Conclusions
CINV still represents a considerable
burden from a clinical point
of view (for example, worse
clinical outcomes because of
reduced patient compliance
to the prescribed cycles of
chemotherapy), from an economic
perspective (for example, avoidable
consumption of healthcare and
non-healthcare resources to deal
with CINV) and from the point of
view of patients and caregivers
given the negative impact on
patients’ quality of life. For
these reasons, it is particularly
crucial to develop new treatment
strategies to fight nausea and
vomiting in patients undergoing
chemotherapy. However, these
new therapies would need
to be evaluated also from a
pharmacoeconomic perspective,
in order to test their cost-
effectiveness and ultimately ensure
that the incremental costs of
innovation are outweighed by the
additional benefits to both patients
and healthcare systems.
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