HPE Managing CINV pocket guide 2019 | Page 3

Contents MECHANISMS 5 CINV: pathophysiology and mechanisms Sandra Melville GUIDELINES 13 Improving adherence and clinical outcomes Alex Molassiotis RISK FACTORS 25 Risk factors and incidence of CINV George Dranitsaris CLINICAL BURDEN 33 Clinical burden of CINV Meinolf Karthaus PHARMACOECONOMICS 43 Economic burden of CINV Rosanna Tarricone TREATMENT 51 Current status and future considerations in treatment Tiene Bauters DRUG–DRUG INTERACTIONS 69 Drug-drug interactions of the main antiemetic agents Snežana Bošnjak and Sandra Vezmar Kovacevic PHARMACY 81 The role of the specialist pharmacist Carl Booth and Saul Parkinson This handbook has been supported with a restricted educational grant by Helsinn, whose involvement was limited to a courtesy review and whose views are not necessarily those expressed in the handbook. hospitalpharmacyeurope.com | 2019 | 3