CONTENTS
INTRODUCTION
3 Alpha 1 Antitrypsin Deficiency: A special type of COPD
Kenneth Chapman
BIOCHEMISTRY
6 Biochemical properties of Alpha 1 Antitrypsin
Oliver McElvaney and Noel McElvaney
EPIDEMIOLOGY
10 Searching for a needle in a haystack
Stefania Ottaviani, Angelo Corsico and Ilaria Ferrarotti
13
QUALITY OF LIFE
Impact of AATD on daily activities and quality of life
Robert Sandhaus
TREATMENT
16 Evidence for AATD treatment
Joanna Chorostowska-Wynimko and Pawel Kuca
Content Director, Secondary Care
Andrea Porter
Art Director
James Depree
Group Sales Director
Edward Burkle
Cover image
Science Photo Library